A. Padmaja, A. Sultana, Khaleequr Rahman, Sumana Nagapattinam
{"title":"Effectiveness of Cyperus scariosus and Boswellia serrata on quality of life in women with stress urinary incontinence assessed with ICIQ-SF -","authors":"A. Padmaja, A. Sultana, Khaleequr Rahman, Sumana Nagapattinam","doi":"10.5455/JEIM.240614.OR.107","DOIUrl":null,"url":null,"abstract":"Objective: To investigate and compare the efficacy of oleo-gum-resin of root of Cyperus scariosus and Boswellia serrata with placebo in improving health related quality of life (HRQOL) in women with stress urinary incontinence (SUI). Methods: A parallel, randomized placebo-controlled, single-blind, pre- and post-test trial was conducted in the National Institute of Unani Medicine Hospital. The patients (n = 60) were randomly allocated to either test (n = 30) or control group (n = 30). In the test and placebo group, equal quantity of C.scariosus and B.serrata (4 g powder in two divided doses) plus pelvic floor muscle training (PFMT) and placebo plus PFMT, respectively, was given for 8 weeks. The outcome was to assess HRQOL by International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF). Mann-Whitney, Wilcoxon Matched paired, Chi-square or Fisher Exact tests were used to analyze the results. Results: The mean ICIQ-SF score in the test and control group at baseline was 10.2 ± 0.96 and 10.13 ± 0.89 respectively. At post-intervention, statistically significant improvement was recorded in the ICIQ-SF scores between groups. In addition, within the group comparison was statistically significant in both groups at each follow up. The percentage improvement from baseline at 12 weeks was 70% and 53% in the test and control groups, respectively. No adverse effects were noted. Conclusion: The test group yielded a more positive effect with regards to improvement in HRQOL than control group in women with stress urinary incontinence. Hence, test drugs plus PFMT appear to be a better alternative than PFMT alone.","PeriodicalId":16091,"journal":{"name":"Journal of Experimental and Integrative Medicine","volume":"78 1","pages":"212-219"},"PeriodicalIF":0.0000,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Experimental and Integrative Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5455/JEIM.240614.OR.107","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: To investigate and compare the efficacy of oleo-gum-resin of root of Cyperus scariosus and Boswellia serrata with placebo in improving health related quality of life (HRQOL) in women with stress urinary incontinence (SUI). Methods: A parallel, randomized placebo-controlled, single-blind, pre- and post-test trial was conducted in the National Institute of Unani Medicine Hospital. The patients (n = 60) were randomly allocated to either test (n = 30) or control group (n = 30). In the test and placebo group, equal quantity of C.scariosus and B.serrata (4 g powder in two divided doses) plus pelvic floor muscle training (PFMT) and placebo plus PFMT, respectively, was given for 8 weeks. The outcome was to assess HRQOL by International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF). Mann-Whitney, Wilcoxon Matched paired, Chi-square or Fisher Exact tests were used to analyze the results. Results: The mean ICIQ-SF score in the test and control group at baseline was 10.2 ± 0.96 and 10.13 ± 0.89 respectively. At post-intervention, statistically significant improvement was recorded in the ICIQ-SF scores between groups. In addition, within the group comparison was statistically significant in both groups at each follow up. The percentage improvement from baseline at 12 weeks was 70% and 53% in the test and control groups, respectively. No adverse effects were noted. Conclusion: The test group yielded a more positive effect with regards to improvement in HRQOL than control group in women with stress urinary incontinence. Hence, test drugs plus PFMT appear to be a better alternative than PFMT alone.