Carla Recupero, Stefano Cacciatore, M. Bernardi, A. M. Martone, F. Landi
{"title":"Multidisciplinary Care for Patients with Cardiac Amyloidosis: a Lesson from the 2023 American College of Cardiology Expert Consensus","authors":"Carla Recupero, Stefano Cacciatore, M. Bernardi, A. M. Martone, F. Landi","doi":"10.24969/hvt.2023.388","DOIUrl":null,"url":null,"abstract":"Amyloidosis is a rare and varied group of diseases defined by the misfolding, aggregation, and deposition of highly structured fibrils made of low molecular weight protein subunits known as amyloid deposits throughout different tissues. Depending on their form and location, amyloid deposits can produce a variety of clinical manifestations resulting in considerable morbidity, death, and a deterioration in quality of life. \"Cardiac amyloidosis\" refers to the clinical condition associated with cardiac amyloid infiltration of the heart. The American College of Cardiology has issued an expert consensus addressing cardiological management of cardiac amyloidosis, the need for an interdisciplinary approach to extra-cardiac manifestations and highlighting the importance of removing barriers to equitable care for patients with amyloidosis. In this editorial we summarize and discuss on relevant issues addressed in the consensus.","PeriodicalId":32453,"journal":{"name":"Heart Vessels and Transplantation","volume":"31 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Heart Vessels and Transplantation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24969/hvt.2023.388","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Amyloidosis is a rare and varied group of diseases defined by the misfolding, aggregation, and deposition of highly structured fibrils made of low molecular weight protein subunits known as amyloid deposits throughout different tissues. Depending on their form and location, amyloid deposits can produce a variety of clinical manifestations resulting in considerable morbidity, death, and a deterioration in quality of life. "Cardiac amyloidosis" refers to the clinical condition associated with cardiac amyloid infiltration of the heart. The American College of Cardiology has issued an expert consensus addressing cardiological management of cardiac amyloidosis, the need for an interdisciplinary approach to extra-cardiac manifestations and highlighting the importance of removing barriers to equitable care for patients with amyloidosis. In this editorial we summarize and discuss on relevant issues addressed in the consensus.
淀粉样变性是一种罕见而多样的疾病,其特征是由低分子量蛋白质亚基组成的高结构原纤维在不同组织中错误折叠、聚集和沉积,即淀粉样沉积。淀粉样蛋白沉积的形式和位置不同,可产生多种临床表现,导致相当高的发病率、死亡和生活质量下降。“心脏淀粉样变性”是指与心脏淀粉样蛋白浸润相关的临床状况。美国心脏病学会(American College of Cardiology)发布了一项专家共识,讨论了心脏淀粉样变的心脏病学管理,需要跨学科的方法来治疗心脏外表现,并强调了消除淀粉样变患者公平护理障碍的重要性。在这篇社论中,我们总结和讨论了共识中涉及的相关问题。