Juvenile-Onset Recurrent Respiratory Papillomatosis

Abstract

Juvenile onset Recurrent Respiratory Papillomatosis (JoRRP) is a condition in which benign papillomata develop and recur in the larynx. JoRRP usually develops in infancy or early childhood (median age=4 years). It is the most common benign neoplasm of the larynx in children. Common presenting symptoms include: stridor, chronic cough, recurrent pneumonia, failure to thrive, dyspnoea, dysphagia and acute respiratory distress in children with upper respiratory tract infection.. In about one third of children with JoRRP the disease spreads into the trachea and bronchi, with the risk of respiratory obstruction. Malignancy is a rare but recognised development in RRP.