Role of zinc-aspirin metal coordination complex in diabetic cataract induced in vitro in goat eye lens

Abstract

Diabetes is one of the major health problems that affect a large number of human populations. Diabetic cataract is one of the most frequent ocular complications rising secondarily to the diabetes. Aspirin and its various coordination metal complex plays a significant role in reduction of diabetes as well as cataract. In this work it had been tried to find about role of the Zinc-Aspirin complex and its effect on diabetic cataract induced by fructose. The synthesized complex had been synthesized using Zinc chloride and Aspirin. The synthesized complex had shown to reduce the in vitro diabetic cataract induced by the fructose. It could be concluded that zinc-aspirin metal complex may significantly reduce the cataractogenesis caused by the diabetes in in vitro model of cataratogenesis.