Study of Microalbuminuria in subjects with Type 2 Diabetes with Ischemic heart disease in Rural population in South India

Indumathi Shankaraiah, N. Kiran
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Abstract

Objectives: Ischemic heart disease (IHD) is the frequent causes of morbidity and mortality worldwide. The prevalence of ischemic heart disease in general population being 2-4%, while in people with type 2 diabetes 9.9% .This study was conducted at Subbaiah Medical College & Research Institute, Shimoga to Study Microalbuminuria in subjects with Type 2 Diabetes mellitus with Ischemic heart disease and without Ischemic heart disease, to assess the cardiovascular health status and to take appropriate steps to prevent further morbidity Methods: We studied 100 patients admitted to Medical wards after meeting the required criteria following investigations was carried out. 1) 12 Lead ECG 2) Spot urine albumin creatinine ratio 3) FBS & PPBS 4) Blood urea and serum creatinine 5) TMT / 2D ECHO 6) Lipid profile. Results: 100 subjects were included, 59% were males and remaining 41% were females.50 subjects were having Type 2 Diabetes with IHD considered as cases, other 50 subjects were having Type 2 Diabetes without IHD considered as controls. Among patients with IHD, maximum UACR value is 276 and minimum value is 20, whereas in patients without IHD, maximum is 42 and minimum is 18.There is significant difference in the mean UACR among patients with and without IHD . T-statistics -7.73 indicates statistically significant with p-value of <0.001 at 5% significance level. Conclusion: Subjects with Type 2 DM with IHD have been found to have higher UACR levels than those subjects without IHD. Screening for UACR can help clinicians estimate a patient's CVD risk and to take appropriate steps to prevent further morbidity.
印度南部农村2型糖尿病合并缺血性心脏病患者微量白蛋白尿的研究
目的:缺血性心脏病(IHD)是世界范围内发病率和死亡率的常见原因。缺血性心脏病在普通人群中的患病率为2-4%,而2型糖尿病患者的患病率为9.9% .本研究在下志县Subbaiah医学院和研究所进行,研究2型糖尿病合并缺血性心脏病和非缺血性心脏病受试者的微量白蛋白尿,以评估心血管健康状况并采取适当措施预防进一步发病率。我们研究了100名在调查后符合要求标准的住院病人。1) 12心电图导联2)尿白蛋白肌酐比值斑点3)FBS和PPBS 4)尿素和血清肌酐5)TMT / 2D ECHO 6)血脂。结果:纳入100例受试者,其中男性59%,女性41%。50例2型糖尿病伴IHD患者作为病例,另外50例2型糖尿病伴IHD患者作为对照。IHD患者UACR最大值为276,最小值为20,而非IHD患者UACR最大值为42,最小值为18。IHD患者和非IHD患者的平均UACR有显著差异。T-statistics为-7.73,在5%显著性水平下p值<0.001。结论:主题与2型DM IHD已经发现没有IHD UACR水平高于这些学科。筛查UACR可以帮助临床医生估计患者的心血管疾病风险,并采取适当措施防止进一步发病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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