Primary study of five predictive outcome scores for neonatal congenital diaphragmatic hernia

Q4 Medicine

中华小儿外科杂志 Pub Date : 2020-01-15 DOI:10.3760/CMA.J.ISSN.0253-3006.2020.01.007

Jingna Li, Lishuang Ma, Ying Wang, Chao Liu, Simiao Yu, Yan-dong Wei, Yanxia Zhang, Yue Zhang

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Abstract

Objective To explore the efficacy and application of five predictive outcome scores for neonatal congenital diaphragmatic hernia (CDH). Methods Clinical data were reviewed for 65 CDH neonates from September 1992 to February 2018. They were divided into survival and death groups based upon the prognosis. Postpartum variables were collected and compared by five scores. The overall scores, degree of illness and combination models were statistically analyzed for selecting the optimal evaluation model. Results Overall scores: SNAP-Ⅱyielded the best performance (AUC=0.813). Degree of illness: SNAP-Ⅱand Brindle obtained decent outcomes (AUC=0.803 & 0.725). However, SNAP-Ⅱfared better. Combination models: SNAP-Ⅱ+ Brindle proved to be the best one (AUC=0.841). Conclusions SNAP-Ⅱachieves the best performance among five predictive outcome scores. And the second one is Brindle. Both may be used for guiding clinical practice for CDH neonates nowadays. Key words: Infant, newborn; Congenital diaphragmatic hernia; Scoring model; Prognosis

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新生儿先天性膈疝五项预测预后评分的初步研究

目的探讨新生儿先天性膈疝(CDH) 5种预后预测评分的疗效及应用。方法回顾性分析1992年9月至2018年2月65例CDH新生儿的临床资料。根据预后分为生存组和死亡组。收集产后变量，按5分进行比较。对综合得分、病情程度、组合模型进行统计分析，选择最优评价模型。结果综合评分:SNAP-Ⅱ表现最佳(AUC=0.813)。疾病程度:SNAP-Ⅱ和Brindle获得了良好的结果(AUC=0.803 & 0.725)。然而，SNAP-Ⅱ表现更好。组合模型:SNAP-Ⅱ+ Brindle为最佳组合模型(AUC=0.841)。结论SNAP-Ⅱ在5个预测结局评分中表现最佳。第二个是Brindle。两者均可用于指导新生儿先天性先天性心脏病的临床实践。关键词:婴幼儿;新生儿;先天性膈疝;评分模型;预后

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来源期刊

中华小儿外科杂志 Medicine-Pediatrics, Perinatology and Child Health

CiteScore

0.40

自引率

0.00%

发文量

8707

期刊介绍： Chinese Journal of Pediatric Surgery is an academic journal sponsored by the Chinese Medical Association. It mainly publishes original research papers, reviews and comments in this field. The journal was founded in 1980 and is included in well-known databases such as Peking University Journal (Chinese Journal of Humanities and Social Sciences) and CSCD Chinese Science Citation Database Source Journal (including extended version). It is one of the national key academic journals under the supervision of the China Association for Science and Technology. Chinese Journal of Pediatric Surgery enjoys a high reputation and influence in the academic community. The articles published in this journal have a high academic level and practical value, providing readers with a large number of practical cases and industry information, and have received widespread attention and citations from readers.