Dias Vc, Silva Vl, Diniz Cg, A. B. Ferreira-Machado, Bastos Vqa, Bastos Rv, Bastos Lqa, Bastos An
{"title":"Pregnant with COVID-19 and Rubella: Impact in the Maternal and Newborn Health","authors":"Dias Vc, Silva Vl, Diniz Cg, A. B. Ferreira-Machado, Bastos Vqa, Bastos Rv, Bastos Lqa, Bastos An","doi":"10.26420/austinjclinimmunol.2021.1042","DOIUrl":null,"url":null,"abstract":"Since December 2019, COVID-19 has become major global public health problem. The understanding of SARS-CoV-2, especially the effect on pregnant women and neonates, is still not fully elucidated. This report case describes a pregnant with COVID-19 and rubella. SARS-CoV-2 nucleic acid was not detected in the neonate just after birth, indicating that there was not vertical transmission. Although anti-SARS-CoV-2 Immunoglobulin G (IgG) antibody and anti-Rubella Virus IgG antibody were detected in the newborn serum, anti-SARS-CoV-2 (Immunoglobulin M) IgM and anti-Rubella Virus IgM were not detected. The observations may suggest transplacental transmission of coronavirus and rubella antibodies, ensuring immediate immunity against these pathogens to newborn.","PeriodicalId":90446,"journal":{"name":"Austin journal of clinical immunology","volume":"23 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Austin journal of clinical immunology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26420/austinjclinimmunol.2021.1042","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Since December 2019, COVID-19 has become major global public health problem. The understanding of SARS-CoV-2, especially the effect on pregnant women and neonates, is still not fully elucidated. This report case describes a pregnant with COVID-19 and rubella. SARS-CoV-2 nucleic acid was not detected in the neonate just after birth, indicating that there was not vertical transmission. Although anti-SARS-CoV-2 Immunoglobulin G (IgG) antibody and anti-Rubella Virus IgG antibody were detected in the newborn serum, anti-SARS-CoV-2 (Immunoglobulin M) IgM and anti-Rubella Virus IgM were not detected. The observations may suggest transplacental transmission of coronavirus and rubella antibodies, ensuring immediate immunity against these pathogens to newborn.