Importance of Cardiopulmonary Bypass Period on Systemic Inflammatory Response.

O. Gokalp, N. Yesilkaya, Y. Beşir, H. Iner, L. Yılık, G. Gokalp, A. Gurbuz
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引用次数: 2

Abstract

We would like to mention the study of Geyik et al. about coronary bypass (CBP) period and systemic inflamatory response is very interesting and useful.1) As the authors stated, strong systemic inflammatory response takes place due to mediators caused by contact of blood and extracorporeal surface during CBP, myocardial ischemia reperfusion secondary to aortic cross-clamping (ACC), endotoxemia and operative trauma.2–4) It is obviously seen that CBP is the most important factor among these. Related to that, when the study of Geyik et al. is considered, there is a general standardization of perioperative data between two groups that are distinguished up to operation period. However, we claim that there shouldn’t be any difference also in between CBP periods and between ACC periods in order to have a reliable comparison in terms of systemic inflamatory response; because many studies revealed that systemic inflammatory response is increased by longer periods of CPB and ACC.3–5) In this point, we suggest that the study would be more valuable if the authors share these data with us.
体外循环周期对全身炎症反应的重要性。
值得一提的是Geyik等人关于冠状动脉搭桥术(CBP)期间和全身炎症反应的研究非常有趣和有用。1)正如作者所述,CBP期间血液和体外表面接触引起的介质、主动脉交叉夹持(ACC)继发心肌缺血再灌注、内毒素血症和手术创伤等因素都会引起强烈的全身炎症反应。2 - 4)显然,CBP是其中最重要的因素。与此相关的是,当考虑Geyik等人的研究时,两组之间的围手术期数据普遍标准化,直至手术期。然而,我们认为在CBP期和ACC期之间不应该有任何差异,以便在全身炎症反应方面有一个可靠的比较;因为许多研究表明,CPB和acc持续时间越长,全身炎症反应增加。3 - 5)在这一点上,我们认为如果作者与我们分享这些数据,这项研究将更有价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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