Optical coherence tomography of living and fabricated microfluidic systems

Abstract

Optical coherence tomography provides high-resolution, real-time data acquisition of both microstructure and function in living and fabricated microfluidic systems. As fabricated microfluidic devices become more complex 3D systems with active and passive components, OCT has the potential to non-invasively assess performance, thus enabling improved design. In this post-genomic period of research, OCT has the potential to aid in the identification of not only morphological mutations, but also functional mutations in developmental biology.