Dispersion liquid microextraction of fluoroquinolones

Q4 Chemistry

Voprosy Khimii i Khimicheskoi Tekhnologii Pub Date : 2023-05-01 DOI:10.32434/0321-4095-2023-147-2-90-98

I. Kushchenko, M. Zui

引用次数: 0

Abstract

The dispersive liquid-liquid microextraction method of norfloxacin, ciprofloxacin and enrofloxacin with chromatographic detection was developed. The optimization of dispersive microextraction was carried out, and the optimal parameters were determined as follows: 5 ml of aqueous solution; 70 l of chloroform; 500 l of isopropanol; extraction time of 5 min; centrifugation time of 5 min; and pH 7.0–9.0. The concentration range was 4.0–100 g/ml, and the limit of detection was not exceeded 1.5 g/ml. The microextraction method was tested on mineral water samples by the standard addition method. The obtained results indicate sufficient accuracy and reproducibility of the developed method. The relative standard deviation does not exceed 2%.

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氟喹诺酮类药物的分散液微萃取

建立了液相色谱法分离诺氟沙星、环丙沙星和恩诺沙星的分散液液微萃取方法。对分散微萃取工艺进行优化，确定最佳工艺参数为:5 ml水溶液;70l氯仿;500l异丙醇;提取时间5 min;离心时间5 min;pH 7.0-9.0。浓度范围为4.0 ~ 100g/ml，检出限不超过1.5g/ml。采用标准加入法对矿泉水样品进行了微萃取试验。所得结果表明，所建立的方法具有足够的准确性和重复性。相对标准偏差不超过2%。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Voprosy Khimii i Khimicheskoi Tekhnologii Chemical Engineering-Chemical Engineering (all)

CiteScore

0.90

自引率

0.00%

发文量

期刊介绍： Voprosy Khimii i Khimicheskoi Tekhnologii (Issues of Chemistry and Chemical Technology) is published bimonthly by the Ukrainian State University of Chemical Technology and accepts Ukrainian- or English language high-quality original articles and reviews concerning various fields of research in chemistry and chemical engineering. Our unusual title “Voprosy khimii i khimicheskoi tekhnologii” originates from the transliterated initial Russian title “Issues of Chemistry and Chemical Technology“. The fact of the matter is that Voprosy khimii i khimicheskoi tekhnologii was founded in 1965 as a scientific journal mainly for Russian-reading and Russian-speaking readership when «the Iron Curtain» existed. Since 1991, after Ukraine declared its independence, our Journal began to publish the articles in Ukrainian and English. Multilingualism is our established tradition. We remember and cherish our traditions, but we follow the latest trends in modern science. Papers that are multidisciplinary or address new or emerging areas of chemistry and chemical engineering are particularly encouraged. Thus, the scope is dynamic. It includes but is not limited to the traditional areas of general, inorganic, organic, analytical, physical chemistry and electrochemistry, as well as all conventional areas of chemical engineering (chemistry of high molecular compounds, technology of inorganic and organic substances, processing of combustible minerals, chemical technology of silicates, processes and apparatus of chemical productions, etc.). The Journal publishes papers dealing with newer interdisciplinary areas such as materials science, nano-science, catalysis, computational and theoretical chemistry, surface phenomenon and colloidal systems, environmental chemistry, green chemistry.