Effects of bacterial PHBV-conduit used for nerve regeneration on oxidative stress parameters in rats

Abstract

in or its on antioxidant by electrospinning and conduits formed by using the nanofiber the of a 1 cm gap in the peritoneal PHBV conduits sacri 17th week after the operations. (MDA), oxidation protein products (AOPP), glutathione and superoxide dismutase of as as surrounding of conduits and serums were measured. Compared to control groups, MDA, AOPP and GSH levels and SOD activites in all graft group serums showed a significant increase, while only MDA and AOPP levels in tissues were statistically higher. Therefore, these findings suggest that PHBV nerve graft used for sciatic nerve defects may lead to oxidative stress in rats.