Management of Positive Cervical Lymph Nodes in Parotid Cancer

Z. Ali, Morsy Aieat, M. Osama, Hussien Marwa, A. Ebrahim
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Abstract

Objective: Assessment the management of positive cervical lymph nodes in parotid cancer. Associated clinical symptoms, histological types, regional lymph node stage (n stage), occult metastasis, neck dissection by level, recurrence, neck irradiation. Methods. We carried out a retrospective analysis of 43 patient’s pathological positive lymph nodes metastatic from parodied cancer, who underwent neck dissection. treated in years 2010-2020, we analyzed the following parameters: age, sex, pT-Status, tumour size, skin invasion, facial nerve palsy, tumour fixation, extraparotid extension, localization, grade, histology, Distribution of T classification was: T3 (60%), and T4 (40%). Results: Mean patient age was 52 years, the most common location of cervical Nodes Met. was level II (72%), then III (49%) then I (42%), then IV (40%) and V (19%). The incidence was highest among patients with (27.9%) mucoepidermoid carcinoma was most common, followed by (14.6%) carcinoma ex-pleomorphic adenoma (9.3%) with acinic cell carcinoma (7%) with squamous cell carcinoma, (11.6%) with adenoid cystic carcinoma, (7.0%) with adenocarcinoma, (7.4%) salivary duct carcinoma, When classified by histological grade, 35% of patients with low/intermediate-grade versus 65.0% high-grade ., Pre-operative fine needle aspiration (83.7%) patients, Post-surgical irradiation was performed in all 43 patients (100%). The resection status (R) was Negative margins R0. (93%), lymphovascular space invasion (44.2%) and (25.6%) had perineural invasion. Skin invasion in (14%) patients, and (4.7%) had regional nodal recurrence (7%) patients with pN1, vs (93%) patients with pN2. Pathologically positive lymph node 4 (range: 1–8 Nodes) lymph nodes harvest 29(range, 23–41 lymph nodes)., Conclusion: modified Radical Neck Dissection with additional radiotherapy should be carried out in patients. Nodes positive parotied cancer especially High histological stage, advanced stage, perineural invasion, positive operative edge, a fixed mass with extra parotid extension facial-nerve paralysis and tumor pain in partied cancer.
腮腺癌颈部淋巴结阳性的处理
目的:探讨腮腺癌颈部淋巴结阳性的处理方法。相关临床症状,组织学类型,局部淋巴结分期(n期),隐匿转移,颈部清扫,复发,颈部放疗。方法。我们对43例接受颈部清扫术的模仿癌病理阳性淋巴结转移患者进行回顾性分析。在2010-2020年间,我们分析了以下参数:年龄,性别,pt状态,肿瘤大小,皮肤侵犯,面神经麻痹,肿瘤固定,腮腺外延伸,定位,分级,组织学。T分类分布为:T3(60%)和T4(40%)。结果:患者平均年龄为52岁,宫颈淋巴结最常见的部位均满足。为II级(72%)、III级(49%)、I级(42%)、IV级(40%)和V级(19%)。以黏液表皮样癌发生率最高(27.9%),其次为癌前多形性腺瘤(14.6%)、腺泡细胞癌(9.3%)、鳞状细胞癌(7%)、腺样囊性癌(11.6%)、腺癌(7.0%)、唾液管癌(7.4%)。按组织学分级,低/中级别为35%,高级别为65.0%,术前细针抽吸患者(83.7%);所有43例患者(100%)均进行了术后放疗。切除状态(R)为阴性切缘R0。(93%),淋巴血管间隙侵犯(44.2%),神经周围侵犯(25.6%)。pN1患者有皮肤侵犯(14%),pN2患者有局部淋巴结复发(4.7%),而pN2患者有(93%)。病理阳性淋巴结4个(范围:1-8个淋巴结)淋巴结收获29个(范围:23-41个淋巴结)。结论:改良根治性颈部清扫术加放疗治疗是可行的。淋巴结阳性腮腺癌,组织学分期高、晚期、神经周围浸润、手术边缘阳性、固定肿块伴腮腺外延伸、面神经麻痹、肿瘤疼痛。
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