Computerised tomography brain findings in male patients with alcohol dependence syndrome: A hospital based cross sectional study

Vatsal Suchak, A. Kakunje, Vishwanath Reddy
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Abstract

Background: Alcohol dependence syndrome (ADS) is a set of mental, emotional and physiological effects of drinking alcohol daily. This study aimed to assess the computerised tomography (CT) brain findings in patients with ADS and to compare it with age-matched controls. Aims: To study the relationship of CT-Brain findings in Male patients with alcohol dependence syndrome and compare it with controls. Materials and Methods: This retrospective study was carried out after obtaining clearance from the institution's ethics committee between 1 January 2021 and April 2022. Medical records of 64 patients were examined, of which 32 patients with the diagnosis of ADS who had already undergone CT brain Neuroimaging and 32 age- and sex-matched normal controls, were randomly selected and parameters were compared to look at cortical atrophy, cella media index (CMI), the maximum width of the third, fourth ventricle, frontal subarachnoid space, Evans ratio, the maximum width of the anterior interhemispheric fissure and maximum width of the Sylvian fissure (MSF). Results: The study detected that the mean age of cases was 41.96 years, and in controls, it was 40.91 years with no significant difference. There was a significant difference in the mean level of CMI, the maximum width of the third and fourth ventricle, frontal subarachnoid space, the maximum width of the anterior hemispheric fissure and the MSF amongst the cases compared to controls. Conclusion: Compared to controls, there was a significant change in CT brain findings amongst the ADS patients.
男性酒精依赖综合征患者的计算机断层扫描脑发现:一项基于医院的横断面研究
背景:酒精依赖综合征(ADS)是每天饮酒引起的一系列心理、情绪和生理影响。本研究旨在评估ADS患者的计算机断层扫描(CT)脑部结果,并将其与年龄匹配的对照组进行比较。目的:探讨男性酒精依赖综合征患者ct -脑表现的关系,并与对照组进行比较。材料和方法:本回顾性研究于2021年1月1日至2022年4月期间获得该机构伦理委员会的批准后进行。随机选取64例患者的病历,其中32例已行CT脑神经影像学诊断为ADS的患者与32例年龄、性别匹配的正常对照,比较皮质萎缩、中细胞指数(CMI)、第三、第四脑室最大宽度、额部蛛网膜下腔、Evans比、前半球间裂最大宽度和Sylvian裂最大宽度(MSF)等参数。结果:本组病例平均年龄为41.96岁,对照组平均年龄为40.91岁,差异无统计学意义。CMI的平均水平、第三脑室和第四脑室的最大宽度、额部蛛网膜下腔、前半球裂的最大宽度和MSF与对照组相比有显著差异。结论:与对照组相比,ADS患者的CT表现有显著变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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