{"title":"Dimethyloxobutylphosphonyl dimethylate (dimephosphone). Pharmacological effects. Neurotropic and cerebroprotective properties","authors":"Е. А. Tsishba, M. Maksimov","doi":"10.33920/med-13-2208-18","DOIUrl":null,"url":null,"abstract":"Dimethyloxobutylphosphonyl dimethylate (dimephosphone) is a Russian drug of metabolic action, developed in Kazan in 1952 at the Institute of Organic and Physical Chemistry named after A. E. Arbuzov, Kazan Branch of the Academy of Sciences of the USSR, and at the Department of Pharmacology, Kazan State Medical University. Its novelty and originality are confirmed by patents in many countries. [2] The paper presents a review of the literature, which confirms that dimephosphone is able to restore damaged brain structures, improves cerebral circulation, and has neurotropic and cerebroprotective properties.","PeriodicalId":12259,"journal":{"name":"Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology)","volume":"170 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33920/med-13-2208-18","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Dimethyloxobutylphosphonyl dimethylate (dimephosphone) is a Russian drug of metabolic action, developed in Kazan in 1952 at the Institute of Organic and Physical Chemistry named after A. E. Arbuzov, Kazan Branch of the Academy of Sciences of the USSR, and at the Department of Pharmacology, Kazan State Medical University. Its novelty and originality are confirmed by patents in many countries. [2] The paper presents a review of the literature, which confirms that dimephosphone is able to restore damaged brain structures, improves cerebral circulation, and has neurotropic and cerebroprotective properties.
Dimethyloxobutylphosphonyl dimephospmethyl late (dimephosphone)是一种具有代谢作用的俄罗斯药物,于1952年在喀山由苏联科学院喀山分院a . E. Arbuzov命名的有机和物理化学研究所和喀山国立医科大学药学系开发。它的新颖性和原创性在许多国家获得了专利。[2]本文通过文献综述,证实二甲膦能够修复受损的脑结构,改善脑循环,具有嗜神经和脑保护作用。