Retroviruses Integrated their Own Genome into the Germ Line

W. Rodney
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Abstract

When retroviruses have integrated their very own genome into the germ line, their genome is passed directly to a following technology. These endogenous retroviruses (ERVs), contrasted with exogenous ones, now make up five–eight% of the human genome. most insertions have no recognized function and are regularly called "junk DNA". However, many endogenous retroviruses play crucial roles in host biology, which includes control of gene transcription, cellular fusion at some stage in placental development inside the direction of the germination of an embryo
逆转录病毒将自己的基因组整合到种系中
当逆转录病毒将自己的基因组整合到种系中时,它们的基因组直接传递给后续技术。与外源性逆转录病毒相比,这些内源性逆转录病毒(erv)现在占人类基因组的5 - 8%。大多数插入没有公认的功能,通常被称为“垃圾DNA”。然而,许多内源性逆转录病毒在宿主生物学中起着至关重要的作用,包括在胚胎萌发方向的胎盘发育的某些阶段控制基因转录和细胞融合
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