Methicillin-induced nephropathy. A case with linear deposition of IgG and C3 on the tubular-basement-membrane.

Abstract

A case is reported of methicillin-induced acute interstitial lymphocytic nephritis following treatment of a Staphylococcus aureus infection. Direct immunofluorescence showed a linear staining of the tubular basement membrane with anti-IgG and -C3. It is suggested that both cellular and humoral immunologic mechanisms are of pathogenic importance.