Seroprevalence of dengue virus infection by detection of NS1 antigen

Abstract

Dengue is the most common arboviral infection prevalent in India. Aedes aegypti mosquito is the principal vector followed by Aedes albopictus.It presents in three clinical stages. It is diagnosed by detection of NS1 antigen, IgM antibody by ELISA and viral RNA by reverse transcriptase PCR. Early diagnosis and treatment is essential to prevent the complications of Dengue. The study was done in a Government Thiruvannamalai Medical College & Hospital about the seroprevalence from the month July 2021 to December 2021 by detection of NS1 antigen. The seroprevalence was found to be 11.4%.The highest number of patients (38.2%) belong to the age group between 21-40 years. Highest number of positive (39.5%) cases reported in October month.