Ceramic nanomaterials: Preparation and applications in osteoporosis and bone tissue regeneration

IF 0.7 4区材料科学 Q4 METALLURGY & METALLURGICAL ENGINEERING

International Journal of Materials Research Pub Date : 2023-07-19 DOI:10.1557/s43578-023-01101-x

A. John, Apurva M. Shetty, Kshema Salian, Samantha Neha Sequeria, P. R. Sumukh, D. Sukmawati, Gowtham Menon, Shajan Abraham, J. Venkatesan, V. Narayanan

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Abstract

The lives and well-being of individuals have been greatly impacted by bone defects brought on by trauma, tumors, genetic disorders, osteoporosis, etc. Also, in the past few decades, the world's aging population has increased the need for nanotechnology to treat trauma-related bone diseases and tissue damage. To successfully imitate the structures seen in naturally occurring systems, nanoengineered systems can now do so. Hence, much focus and effort have been spent in the last decade on nanotechnology, especially nanomaterials. Ceramic nanomaterials have been widely used in tissue repair and engineering due to their high biocompatibility and reactivity. This review aims to identify and discuss the properties, applications in osteoporosis and bone tissue regeneration, mechanism of action, biocompatibility, drawbacks, and future scopes of a few ceramic nanomaterials, i.e., calcium phosphate, hydroxyapatite, mesoporous silica, and bioactive glass. Images reproduced from sources: Adobe Stock, Wikimedia commons, Vecteezy, and iStock under creative commons (with free-to-reuse permission for noncommercial purposes).

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纳米陶瓷材料的制备及其在骨质疏松和骨组织再生中的应用

由于创伤、肿瘤、遗传疾病、骨质疏松症等引起的骨缺损，极大地影响了人们的生活和健康。此外，在过去的几十年里，世界人口老龄化增加了对纳米技术治疗创伤相关骨病和组织损伤的需求。为了成功地模仿自然系统中的结构，纳米工程系统现在可以做到这一点。因此，在过去的十年中，人们在纳米技术，特别是纳米材料上花费了大量的精力和精力。陶瓷纳米材料以其良好的生物相容性和反应性在组织修复和工程中得到了广泛的应用。本文综述了磷酸钙、羟基磷灰石、介孔二氧化硅和生物活性玻璃等几种纳米陶瓷材料的性能、在骨质疏松症和骨组织再生中的应用、作用机制、生物相容性、缺点和发展前景。图片来源:Adobe Stock, Wikimedia commons, Vecteezy和iStock在creative commons(非商业用途的免费重用许可)下复制。

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来源期刊

International Journal of Materials Research 工程技术-冶金工程

CiteScore

1.30

自引率

12.50%

发文量

119

审稿时长

6.4 months

期刊介绍： The International Journal of Materials Research (IJMR) publishes original high quality experimental and theoretical papers and reviews on basic and applied research in the field of materials science and engineering, with focus on synthesis, processing, constitution, and properties of all classes of materials. Particular emphasis is placed on microstructural design, phase relations, computational thermodynamics, and kinetics at the nano to macro scale. Contributions may also focus on progress in advanced characterization techniques. All articles are subject to thorough, independent peer review.