Breast Cancer in Young Brazilian Women: Challenge for the Oncology Care

Â. Gravena, C. M. D. Agnolo, T. C. R. Lopes, Marcela de Oliveira Demitto, William Augusto de Mello, Deise Helena Pelloso Borghesan, S. C. R. Brischiliari, M. Carvalho, S. Pelloso
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引用次数: 6

Abstract

Objective. To investigate and compare aspects of breast cancer in young women ( 40 years old). Methods. Retrospective, cross-sectional, analytical, and exploratory study based on data from 2009 to 2012 obtained from the Breast Cancer Information System (SISMAMA) and the Unified Health System Information Data (DATASUS). The studied population consisted of women () with malignant breast cancer. The analysed variables were education level, race, nodule detection at the clinical examination or image studies, presence of palpable axillary lymph nodes, surgical approach, and tumor histological type and grade. Results. There was increasing detection of breast cancer cases in young women among the studied years. Young women had more palpable lymph nodes (OR 1.28, 95% CI: 1.18–1.39), ductal carcinoma as the most frequent histologic type (OR 1.36, 95% CI: 1.22 to 1.53), and grades II and III tumor (OR 16.01 , 95% CI: 13.30 to 19.28 ). The lesion detection by clinical examination was higher in women <40 years (OR 1.34, 95% CI: 1.24 to 1.45). Conclusion. Although there are early detection measures related to breast cancer, they are not the usual practice of the young female public, suggesting the need for a review of existing public policies in the country.
巴西年轻女性乳腺癌:肿瘤治疗的挑战
目标。调查和比较年轻女性(40岁)乳腺癌的各个方面。方法。基于2009 - 2012年乳腺癌信息系统(SISMAMA)和统一卫生系统信息数据(DATASUS)数据的回顾性、横断面、分析性和探索性研究。研究人群包括患有恶性乳腺癌的妇女。分析的变量包括受教育程度、种族、临床检查或影像学检查中结节的发现、是否存在可触及的腋窝淋巴结、手术入路、肿瘤的组织学类型和分级。结果。在研究期间,年轻女性乳腺癌病例的检出率有所上升。年轻女性有更多可触及的淋巴结(OR 1.28, 95% CI: 1.18-1.39),导管癌是最常见的组织学类型(OR 1.36, 95% CI: 1.22 - 1.53), II级和III级肿瘤(OR 16.01, 95% CI: 13.30 - 19.28)。临床检查的病变检出率在<40岁的女性中较高(OR: 1.34, 95% CI: 1.24 ~ 1.45)。结论。虽然有与乳腺癌有关的早期检测措施,但这并不是年轻女性公众的通常做法,这表明有必要审查该国现有的公共政策。
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