INFLUENCE OF THE PREPARATION BASED ON BUTAPHOSPHANE AND CYANOCOBALAMIN ON THE PHYSIOLOGICAL AND FUNCTIONAL STATE OF THE ORGANISM OF WEANLED PIGLETS

Abstract

The article presents the results of clinical trials of a veterinary medicinal product based on butaphosphane and cyanocobalamin on weaned piglets during the growing period with signs of anemia. The drug was used in the dosage recommended by the manufacturer - intramuscularly in a dose of 2.0 ml per animal, once a day, for 5 days. Blood for laboratory research was taken from animals before and after the use of the drug. Research of hematological and biochemical parameters was carried out according to generally accepted methods. The therapeutic effectiveness of the drug was evaluated by comparing it with the data obtained before the start of treatment. Based on the obtained data and their statistical analysis, conclusions were made about the effect of the drug on the morpho-functional state of the piglets' body. A comparative analysis of hematological indicators of piglets before and after the use of the drug showed optimization of the leukogram, which was a sign of improvement in the physiological condition of the animals. Activation of hematopoietic processes was noted, confirmed by indicators of red blood of piglets. The biochemical profile of the blood serum of experimental animals after treatment showed a positive effect on indicators of mineral and protein metabolism and the state of the hepatobiliary system. Based on the assessment of the clinical condition of the animals and the obtained results of laboratory studies, it was established that the tolerability of the studied drug when administered to piglets with signs of anemia was good, no changes in the behavior of the piglets were detected. Side effects and negative phenomena have not been established. Monthly monitoring of the clinical condition of piglets confirmed the safety of the drug when used in the dosage and method of administration recommended by the manufacturer. The results of hematological and biochemical studies confirmed the positive effect of the drug on the body and its effectiveness in the treatment of the anemic state of piglets and the correction of the physiological state of piglets.