Ophthalmic findings in Yusho

Journal of Dermatological Science Supplement Pub Date : 2005-04-01 DOI:10.1016/j.descs.2005.03.009

Takahiko Nakamura , Miho Miyazaki , Yoshitaka Ohnishi , Tatsuro Ishibashi , on behalf of the Study Group for Yusho

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引用次数: 2

Abstract

Background:

The ocular signs in Yusho include hypersecretion by the meibomian glands, abnormal pigmentation of the bulbar conjunctiva, unusual pigmentation of the limbal conjunctiva, pigmentation of the tarsal conjunctiva and edema of the eyelid.

Participants and methods:

The ocular symptoms in Yusho patients were analyzed to investigate their relationship with the concentration of dioxins in the blood. The participants were patients with Yusho who underwent examinations including measurement of blood dioxin levels and ocular symptoms in 2002.

Results and conclusion:

The significant relation between the increase in ocular discharge and the level of polychlorinated dibenzofurans (PCDFs) in the blood is currently considered strong. No significant relationship with blood PCDF levels was found with any of the other four ocular symptoms. Although the blood levels of polychlorinated biphenyls (PCBs) and dioxins are now decreasing in Yusho patients, they still cause abnormal discharge from the eye.

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玉树眼科的发现

背景:玉树患者的眼部体征包括睑板腺分泌亢进、球结膜色素沉着异常、缘结膜色素沉着异常、跗骨结膜色素沉着和眼睑水肿。研究对象和方法:分析玉树患者眼部症状与血中二恶英浓度的关系。参与者是2002年接受了包括血液二恶英水平和眼部症状测量在内的检查的Yusho患者。结果与结论:目前认为眼分泌物增加与血液中多氯二苯并呋喃(PCDFs)水平有很强的相关性。血液PCDF水平与其他四种眼部症状均无显著关系。尽管玉树病人血液中多氯联苯和二恶英的含量正在下降，但它们仍然会导致眼睛分泌物异常。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Dermatological Science Supplement

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