Laser, Intense Pulsed Light, and Radiofrequency for the Treatment of Burn Scarring: A Systematic Review and Meta-Analysis

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-03-23 DOI:10.3390/ebj4020013

Yubing Bai, Yiqiu Zhang, Wei Ni, M. Yao

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引用次数: 0

Abstract

Burns and scarring are considered some of the greatest problems in public health because of their frequent occurrence. Today, photo-electric technology shows promising results in the treatment of burn scars. Over the years, more clinical trials and more technologies for scarring have emerged. The aim of this study was to determine better timing and methods of photo-electric therapy for burn scars. This study was registered in PROSPERO (CRD42023397244), following the PRISMA statement, and was carried out in concordance with the PRISMA checklist. In October 2022, we searched PubMed.gov, Embase, and the Cochrane library (1980–present) for published studies related to the photo-electric treatment of burn scars. Two review authors independently selected the studies, extracted the data, assessed the risk of bias among the studies included, and carried out NIH assessments to assess the certainty of the evidence. A third review author arbitrated any disagreements. Our research included 39 studies. We found evidence suggesting that photo-electric therapy between six months and one year offers significantly better outcomes than treatment of scarring after one year. The evidence also suggests the use of IPL for the treatment of early burn scarring. However, it is important to emphasize that the scientific evidence remains insufficient. We need more clinical trials of higher quality and with less heterogeneity to confirm our results.

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激光、强脉冲光和射频治疗烧伤疤痕:系统回顾和荟萃分析

烧伤和疤痕被认为是公共卫生中最严重的问题之一，因为它们经常发生。今天，光电技术在烧伤疤痕的治疗上显示出有希望的结果。多年来，出现了更多的临床试验和更多的疤痕技术。本研究的目的是确定烧伤疤痕更好的光电治疗时机和方法。根据PRISMA声明，本研究已在PROSPERO (CRD42023397244)注册，并按照PRISMA核对表进行。2022年10月，我们检索了PubMed.gov、Embase和Cochrane图书馆(1980年至今)，查找与烧伤疤痕光电治疗相关的已发表研究。两位综述作者独立选择研究，提取数据，评估纳入研究的偏倚风险，并进行NIH评估以评估证据的确定性。第三位综述作者对任何异议进行仲裁。我们的研究包括39项研究。我们发现有证据表明，6个月至1年的光电治疗效果明显好于1年后的疤痕治疗。证据也表明IPL可用于早期烧伤瘢痕的治疗。然而，必须强调的是，科学证据仍然不足。我们需要更多高质量、低异质性的临床试验来证实我们的结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.