Phytochemistry and biological activity of Prosopis fracta

B. Dheeb, S. Hashim, Rawad Kh. Hameed, Shilan W. Hasan
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Abstract

Background: Prosopis fracta is a valuable and useful medicinal plant for the purpose of extracting flavonoids and it is one of the most important plants with medicinal properties. Prosopis fracta is found in many southern regions of Iran. Objective: the aim of this review Phytochemistry and biological activity of Prosopis fracta. Material and Methods: Initially, the powder was degreased by hexane and then after completion of the extraction process, we obtained a rotary solvent removal and the rest of the extract was frozen for retention, then it stored at -23°C. The freeze-dried samples are dissolved in methanol and permanently filtered through a 0.35 syringe filter. Results: Prosopis fracta extracts using to treat cancer, which destroying activity via mitochondrial changes, as showed a good example for increased reactive oxygen species (ROS) levels, SIRT3 activity and cell death in HT-29 related to the intestines and rectum cancer cells. Conclusion: Antimicrobial and phytochemical studies provide valuable insight into understanding media. Sometimes the idea of the route responsible for the activity of these phytochemicals against oxidizing compounds that act as a source of harmful chemical to the body is removal from service of protein and loss of function.  
豆叶植物化学及生物活性研究
背景:槐叶是一种提取黄酮类化合物的有价值的药用植物,是重要的药用植物之一。在伊朗的许多南部地区都发现了Prosopis fracta。目的:综述槐叶植物化学及生物活性的研究进展。材料与方法:先用己烷对粉末进行脱脂,萃取过程完成后,进行旋转溶剂去除,剩余萃取物冷冻保存,-23℃保存。冻干的样品溶解在甲醇中,并通过0.35注射器过滤器永久过滤。结果:用于治疗癌症的Prosopis fracta提取物通过改变线粒体破坏活性,显示出与肠和直肠癌细胞相关的HT-29中活性氧(ROS)水平、SIRT3活性和细胞死亡增加的良好例子。结论:抗菌和植物化学研究为了解培养基提供了有价值的见解。有时,这些植物化学物质对抗氧化性化合物(对身体有害的化学物质的来源)的活性途径的想法是从蛋白质的服务中移除和功能丧失。
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