Varying Presentations of EBV-associated Clinical Entities with Emphasis on EBV-Associated T- and NK-cell Lymphoproliferative Disorders of Childhood

IF 1.8 4区医学 Q3 PATHOLOGY

International Journal of Experimental Pathology Pub Date : 2021-12-29 DOI:10.33696/pathology.2.028

Jonathan Y. Keow, N. Sangle

引用次数: 0

Abstract

The Epstein-Barr Virus (EBV) is an endemic human herpesvirus, with 90% of people demonstrating serological evidence of prior exposure to EBV. In most cases, primary infections of EBV generate mild or asymptomatic clinical courses, but may present as infectious mononucleosis if contracted during young adulthood. In a small percentage of cases, EpsteinBarr virus infection may manifest as a noncanonical reaction, yielding a wide variety of clinical manifestations.

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ebv相关临床实体的不同表现，重点是ebv相关的儿童T和nk细胞淋巴增生性疾病

爱泼斯坦-巴尔病毒(EBV)是一种地方性的人类疱疹病毒，90%的人表现出先前接触过EBV的血清学证据。在大多数情况下，EBV的原发性感染产生轻微或无症状的临床过程，但如果在年轻成年期间感染，可能表现为传染性单核细胞增多症。在一小部分病例中，eb病毒感染可能表现为非典型反应，产生多种临床表现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Experimental Pathology 医学-病理学

CiteScore

4.50

自引率

3.30%

发文量

审稿时长

>12 weeks

期刊介绍： Experimental Pathology encompasses the use of multidisciplinary scientific techniques to investigate the pathogenesis and progression of pathologic processes. The International Journal of Experimental Pathology - IJEP - publishes papers which afford new and imaginative insights into the basic mechanisms underlying human disease, including in vitro work, animal models, and clinical research. Aiming to report on work that addresses the common theme of mechanism at a cellular and molecular level, IJEP publishes both original experimental investigations and review articles. Recent themes for review series have covered topics as diverse as "Viruses and Cancer", "Granulomatous Diseases", "Stem cells" and "Cardiovascular Pathology".