Systemic Lupus Erythematosus in Gynecology

Abstract

Systemic lupus erythematosus is a chronic autoimmune disease that can affect various organs and parts of the body, especially the skin, joints, blood, kidneys, and central nervous system. Systemic lupus erythematosus is not a contagious disease, it is an autoimmune disease in which the immune system loses the ability to distinguish foreign from the patient’s own tissues and cells. The immune system makes mistakes and produces, among other things, autoantibodies that recognize their own cells as foreign and attack them. The result is an autoimmune reaction that causes inflammation. Inflammation means that the affected part of the body becomes warm, red, swollen and sometimes painfully sensitive. If the signs of inflammation are long-lasting, as they may be in the case of systemic lupus erythematosus, tissue damage and its normal function may occur. Therefore, the goal of treatment of systemic lupus erythematosus is to alleviate inflammation. A number of hereditary risk factors along with various environmental factors are thought to be responsible for this impaired immune response. Systemic lupus erythematosus is known to be caused by a variety of factors, including hormonal imbalances during puberty, stress, and environmental factors such as sun exposure, viral infections, and medications.