Novel unsymmetric diimines: Synthesis and biological evaluation against pathogenic microorganisms

Abstract

In this research study, three new unsymmetric diimines (3a-3c) were prepared using a two-step process. The synthesized unsymmetric tetradentate diimines were elucidated by FT-IR, 1H-NMR, LC-MS, elemental analysis techniques. The antimicrobial and the antifungal properties of newly synthesized unsymmetrical diimines (3a-3c) and previously reported by one of us unsymmetrical diimines (4a-4c) were evaluated against L. monocytogenes 4b, B. cereus sp., S. typhi H, Br. abortus, S. epidermis sp., M. Luteus sp., E. coli, P. putida sp. Sh. dys. typ. 7 ve C. albicans. 3b, 3c, 4a and 4c are showed the highest antimicrobial activity against B.cereus sp. 3a and 4b are exhibited the highest activity against S.epidermis sp. and Br. abortus, respectively. In addition, all unsymmetrical diimines are showed high antifungal activity against C. albicans.