Increased prevalence of cardiovascular risk factors in newly diagnosed type 2 diabetes patients - a retrospective study.

G. Roman, G. Teodorescu
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Abstract

Context Identification of CV risk factors from T2DM diagnosis allows optimization of treatment to prevent CV complications and death. Objective The primary objective of the study was to describe the CV risk factors in patients with T2DM at the time of diagnosis and/or therapeutic specific measures taken. Design This was a non-interventional, multicenter, retrospective chart review of newly diagnosed patients with T2DM in 49 study centers in Romania. Subjects and Methods Adults with a diagnosis of T2DM between January - December 2014. Statistical analysis used appropriate descriptive methods. Results 1218 patients were included, mean age (SD) at diagnosis was 59.16 (10.87) years. Half of the patients (54%) presented obesity and 47.7% of patients had arterial hypertension. Overall, 76.2% of subjects had LDL-cholesterol ≥ 100 mg/dL, and 59.1% had triglycerides ≥ 150 mg/dL. The mean glycemia was 198.8 mg/dL (78.3) and 50.2% of patients had HbA1c ≥7%. Sedentary lifestyle in 73.8% of the cases, and 91.3% unhealthy eating habits reported. In addition to diet, 82.2% of patients received anti-diabetes treatment, 62.6% lipid-lowering, and 66.6% anti-hypertensive medication. Conclusion This retrospective study showed a high prevalence of CV risk factors and/or established CV disease at the time of T2DM diagnosis in Romania.
新诊断的2型糖尿病患者心血管危险因素患病率增加——一项回顾性研究
从T2DM诊断中识别CV危险因素可以优化治疗以预防CV并发症和死亡。目的:本研究的主要目的是描述T2DM患者在诊断和/或采取特定治疗措施时的CV危险因素。设计:这是一项对罗马尼亚49个研究中心新诊断的T2DM患者的非介入性、多中心、回顾性图表回顾。研究对象和方法:2014年1 - 12月诊断为2型糖尿病的成年人。统计分析采用适当的描述性方法。结果纳入1218例患者,诊断时平均年龄(SD)为59.16(10.87)岁。一半的患者(54%)表现为肥胖,47.7%的患者有动脉高血压。总体而言,76.2%的受试者ldl -胆固醇≥100 mg/dL, 59.1%的受试者甘油三酯≥150 mg/dL。平均血糖为198.8 mg/dL(78.3), 50.2%的患者HbA1c≥7%。73.8%的病例与久坐不动的生活方式有关,91.3%的病例与不健康的饮食习惯有关。除饮食外,82.2%的患者接受了抗糖尿病治疗,62.6%的患者接受了降脂治疗,66.6%的患者接受了降压药治疗。结论:本回顾性研究显示,罗马尼亚T2DM诊断时CV危险因素和/或已确诊CV疾病的患病率较高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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