Relationship between the Asbestos Cumulative Exposure Index (ACEI) and the Latency Period of Asbestos Related Diseases (ARD) within an Italian Study Group of Ex-Asbestos Workers

Occupational medicine and health affairs Pub Date : 2016-08-05 DOI:10.4172/2329-6879.1000243

G. M. Ferri, C. Guastadisegno, G. Intranuovo, V. Luisi, D. Cavone, B. Licchelli, Elena Viola Buononato, L. Macinagrossa, R. Molinini

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Abstract

Objectives: The association between asbestos exposure, measured by mean of Asbestos Cumulative Exposure Index (ACEI) and the latency period of non-malignant asbestos-related diseases (ARD) diagnosed according to the American Thoracic Society (ATS) criteria was studied. Methods: 306 exposed asbestos workers in Bari, Italy, were included in a health surveillance program. By means of a standardized questionnaire we assessed asbestos exposure through ACEI. Latency period of Asbestos Related Diseases (ARD) was also assessed. Results: We found a significant inverse correlation between latency and ACEI increasing with ARD severity. ACEI and 30-35 years of age at time of first exposure were inversely associated with the latency period. The risk of ARD increased from baseline to the 2nd follow-up and among subjects exposed for the first time before 1960. Conclusions: The most important factors that caused a reduction in the latency period were the year of first exposure and the ACEI score while smoking habits did not show to play a significant role.

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意大利前石棉工人研究组石棉累积暴露指数(ACEI)与石棉相关疾病潜伏期(ARD)的关系

目的:研究石棉累积暴露指数(ACEI)与美国胸科学会(ATS)诊断的非恶性石棉相关疾病(ARD)潜伏期之间的关系。方法:对意大利巴里市306名石棉暴露工人进行健康监测。通过标准化问卷，我们通过ACEI评估了石棉暴露。评估石棉相关疾病潜伏期(ARD)。结果:我们发现潜伏期和ACEI随ARD严重程度的增加呈显著的负相关。ACEI和首次接触时30-35岁与潜伏期呈负相关。从基线到第二次随访以及在1960年之前首次接触的受试者中，ARD的风险增加。结论:导致潜伏期减少的最重要因素是首次暴露年份和ACEI评分，而吸烟习惯没有显示出显著作用。

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Occupational medicine and health affairs

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