A Case of Rheumatic Heart Disease Complicated by Acute Infective Endocarditis and Valve Leaflet Perforation

Minghui Sun, Yuewei Li, Shibo Zhao
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Abstract

Rheumatic Heart Disease (RHD), abbreviated as rheumatic heart disease, is a heart disease caused by repeated attacks or further deterioration of Acute Rheumatic Fever (ARF), which is mostly caused by valve damage (Zhang P & Wang P., 2021). The production of ARF is the result of a series of autoimmune reactions by group A streptococci that invade the pharynx of a susceptible host. Clinically, rheumatic heart disease mostly involves valves, which can cause patients to have a variety of manifestations such as incomplete valve closure or stenosis, structural remodeling of the heart, etc. If patients do not seek medical attention in time to delay the best time for treatment, they often develop acute heart failure, malignant arrhythmias and other acute complications of the cardiovascular system in the later stages of the disease. Clinically, rheumatic heart disease complicated by infective endocarditis is not common, and valve leaflet perforation due to severe infection is even rarer! A case of acute infective endocarditis complicated by atypical rheumatic heart disease and simultaneous valve leaflet perforation in our hospital is reviewed and reported below.
风湿性心脏病并发急性感染性心内膜炎及瓣膜小叶穿孔1例
风湿性心脏病(rheumatatic Heart Disease, RHD),简称风湿性心脏病,是急性风湿热(Acute rheumatatic Fever, ARF)反复发作或进一步恶化引起的心脏病,多由瓣膜损伤引起(张鹏、王鹏,2021)。ARF的产生是a群链球菌侵入易感宿主咽部的一系列自身免疫反应的结果。临床上风湿性心脏病多累及瓣膜,可使患者出现瓣膜关闭不全或狭窄、心脏结构重塑等多种表现。如果患者不及时就医,耽误了治疗的最佳时机,往往会在疾病的后期发展为急性心力衰竭、恶性心律失常等心血管系统的急性并发症。临床上风湿性心脏病合并感染性心内膜炎并不常见,严重感染导致瓣膜小叶穿孔更是罕见!现报告我院一例急性感染性心内膜炎合并不典型风湿性心脏病并发瓣膜小叶穿孔。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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