Biomechanical Properties of Grown Cartilage Are Decreased in the Presence of Retinoic Acid, Chondroitinase ABC and Ibuprofen

Christopher T. Chen, P. Torzilli, K. Fishbein, R. Spencer, W. Horton
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Abstract

The objective of this study was to determine the biomechanical properties of cartilage grown in a hollow-fiber bioreactor and their correlation with biochemical properties and magnetic resonance images (MRT). Engineered/grown cartilage has been shown to be a useful resource for cartilage repair [5]. The integrity and functional strength of engineered tissues are reflected in their biomechanical properties. A better understanding of the biomechanical properties of engineered cartilage can benefit us when designing a system to grow cartilage.
生长软骨的生物力学特性在维甲酸、软骨素酶ABC和布洛芬的存在下降低
本研究的目的是确定在中空纤维生物反应器中生长的软骨的生物力学特性及其与生化特性和磁共振成像(MRT)的相关性。工程/生长软骨已被证明是软骨修复的有用资源[5]。工程组织的完整性和功能强度反映在它们的生物力学特性上。更好地了解工程软骨的生物力学特性可以使我们在设计软骨生长系统时受益。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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