The Eurycoma Longifolia Freeze-Dried Water Extract-Physta® Does not Change Normal Ratios of Testosterone to Epitestosterone in Healthy Males

Abstract

Eurycoma longifolia is traditionally known for its adaptogenic properties and often used for the general well-being and increased performance in daily life. Methods: In a randomized, double blind, placebo-controlled clinical trial, 40 Malaysian men aged 30-55 years performed a battery of physical testings during which the ratio of Testosterone (T) to Epitestosterone (E) was analyzed. The daily intake was 300 mg of the freeze-dried water extract of Eurycoma longifolia root (Physta®, Biotropics Malaysia) or placebo for a period of 12 weeks. Results: At the end of the study the T/E-ratio in the herbal group ranged from 0.03 to 2.95 and was not significantly different from values at baseline (p=0.49). Further, the ratio-values for E. longifolia compared to placebo did not change over time. The weight lifting force which measures muscular strength using back & leg strength test, increased significantly from baseline to end of the study in the herbal group by approximately 14 kg (p=0.0166). Conclusion: The ratios of testosterone to epitestosterone did not change during a 12-weeks E. longifolia intake. The data suggest that this herb does not exhibit “doping”- like effects. Instead, muscular strength improved significantly in the back and leg with E. longifolia supplementation rendering this herb good for physical performance minus the doping effects.