Persistent Hyperbilirubinaemia with Absence of Urinary Bile Salts and Bile Pigments

Abstract

HBsAg negative. was negative for bile salts and bile pigments. dengue with dengue NS1 antigen positive on serum in August 2015 when his urine bile salts and bile pigments became positive and then again subsequently became negative. On presentation to us, he had jaundice. Systemic examination was normal. Liver function tests (LFT) revealed slightly elevated bilirubin with normal serum transaminases and normal albumin. Ultrasound abdomen showed hepatomegaly with normal echotexture of the liver. Fibroscan was normal. Genetic test could not be done due to non-affordability. He was advised yearly liver function tests. Abstract Gilbert Syndrome is a rare benign condition of abnormal bilirubin conjugation. Patients with Gilbert syndrome are usually asymptomatic except for intermittent episode of unconjugated hyperbilirubinaemia, needing no treatment.