{"title":"Can gut flora changes be new biomarkers for depression?","authors":"Ping Lin , Qingtian Li","doi":"10.1016/j.flm.2017.08.002","DOIUrl":null,"url":null,"abstract":"<div><p>Major depressive disorder is a serious mental health condition that involves increasing patients, medical care, economic burden and scientific problems. In these years, a lot of evidence is mounting that gut commensal microflora is a significant modulator in psychological disorders including anxiety and depression. Here we review recent findings about gut-brain-axis as well as their crosstalk and interaction. Gaining a better perception of the relationship between gut flora and the depression and other related diseases, this complex parameter could provide a novel insight into the pathogenesis, clinical diagnosis and treatments in major depressive disorder.</p></div>","PeriodicalId":100555,"journal":{"name":"Frontiers in Laboratory Medicine","volume":"1 3","pages":"Pages 129-134"},"PeriodicalIF":0.0000,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.flm.2017.08.002","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Laboratory Medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2542364917300900","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Major depressive disorder is a serious mental health condition that involves increasing patients, medical care, economic burden and scientific problems. In these years, a lot of evidence is mounting that gut commensal microflora is a significant modulator in psychological disorders including anxiety and depression. Here we review recent findings about gut-brain-axis as well as their crosstalk and interaction. Gaining a better perception of the relationship between gut flora and the depression and other related diseases, this complex parameter could provide a novel insight into the pathogenesis, clinical diagnosis and treatments in major depressive disorder.
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