Exploration du lien entre la confiance diagnostique et l’accord interjuges dans l’évaluation de la sévérité du TAG

G. Marcotte-Beaumier , N.C. Ricard , M.J. Dugas
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La confiance diagnostique fut évaluée par des cliniciens ayant administré indépendamment deux entrevues diagnostiques structurées à 100 patients évalués pour participer à une étude de traitement pour le trouble d’anxiété généralisée. Les résultats révèlent une relation statistiquement significative entre la confiance diagnostique aux deux entrevues indépendantes. Par contre, la confiance diagnostique à chacune des deux entrevues ne corrèle pas avec l’accord interjuges. Lorsque le nombre de troubles comorbides est contrôlé statistiquement, la relation entre la confiance aux deux entrevues n’est plus significative. Il semble donc y avoir une entente sur les tableaux cliniques qui sont plus faciles ou difficiles à diagnostiquer selon le nombre de troubles comorbides.</p></div><div><h3>Background</h3><p>When providing a diagnostic impression, clinicians are guided by their sense of certainty or confidence. 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Our hypotheses were: (1) that diagnostic confidence on an initial diagnostic interview (Anxiety Disorders Interview Schedule for DSM-IV; ADIS-IV) would be correlated with diagnostic confidence on a second independent diagnostic interview (Mini International Neuropsychiatric Interview; MINI); and (2) that higher diagnostic confidence at each interview would be associated with greater inter-rater agreement.</p></div><div><h3>Method</h3><p>As part of a clinical trial for generalized anxiety disorder, we examined whether diagnostic confidence was associated with inter-rater agreement. 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引用次数: 0

Abstract

Lorsqu’un clinicien a une forte confiance en son impression diagnostique, cette dernière est-elle plus fidèle ? Cette étude a pour but d’explorer s’il existe un lien entre la confiance diagnostique du clinicien et la fidélité de son impression diagnostique, tel qu’évaluée par accord interjuges. Nos hypothèses sont les suivantes : (1) la confiance diagnostique à une première entrevue diagnostique structurée sera corrélée avec la confiance diagnostique à une deuxième entrevue diagnostique structurée ; et (2) le degré de confiance diagnostique à chacune des deux entrevues prédira l’accord interjuges. La confiance diagnostique fut évaluée par des cliniciens ayant administré indépendamment deux entrevues diagnostiques structurées à 100 patients évalués pour participer à une étude de traitement pour le trouble d’anxiété généralisée. Les résultats révèlent une relation statistiquement significative entre la confiance diagnostique aux deux entrevues indépendantes. Par contre, la confiance diagnostique à chacune des deux entrevues ne corrèle pas avec l’accord interjuges. Lorsque le nombre de troubles comorbides est contrôlé statistiquement, la relation entre la confiance aux deux entrevues n’est plus significative. Il semble donc y avoir une entente sur les tableaux cliniques qui sont plus faciles ou difficiles à diagnostiquer selon le nombre de troubles comorbides.

Background

When providing a diagnostic impression, clinicians are guided by their sense of certainty or confidence. It would be expected, therefore, that when a clinician is confident in his/her diagnostic impression, the latter should stand a greater chance of being reliable. Surprisingly, some medical studies suggest that there is only a moderate relationship between a clinician's level of confidence in his/her diagnostic impression and the reliability/validity of the diagnosis. Generalized anxiety disorder (GAD) is one of the most difficult psychological disorders to assess and diagnose. Thus, GAD offers a unique opportunity to examine the relationship between clinicians’ diagnostic confidence and the reliability of their diagnostic impression. Our hypotheses were: (1) that diagnostic confidence on an initial diagnostic interview (Anxiety Disorders Interview Schedule for DSM-IV; ADIS-IV) would be correlated with diagnostic confidence on a second independent diagnostic interview (Mini International Neuropsychiatric Interview; MINI); and (2) that higher diagnostic confidence at each interview would be associated with greater inter-rater agreement.

Method

As part of a clinical trial for generalized anxiety disorder, we examined whether diagnostic confidence was associated with inter-rater agreement. Ratings of diagnostic confidence (0 to 100%) were provided by a team psychologist using the ADIS-IV and a team psychiatrist using the MINI following independent administrations of the interviews to 100 patients with GAD.

Results

Correlational analyses revealed a significant association between diagnostic confidence on the ADIS-IV and diagnostic confidence on the MINI (r = 0.23, p < 0.05). However, neither diagnostic confidence on the ADIS-IV nor diagnostic confidence on the MINI was associated with inter-rater agreement between the interviews. Conversely, an exploratory analysis showed that the number of comorbid disorders was related to diagnostic confidence on each interview (ADIS-IV: r = −41, p < .001; MINI: r = −36, p < 0.001), with higher comorbidity being associated with lower confidence. Finally, comorbidity accounted for the relationship between confidence levels on each of the interviews.

Conclusion

The results of this study suggest that clinicians tend to agree on which cases are easier or harder to diagnose based on the number of comorbid disorders present. However, confidence in one's diagnosis appears to be unrelated to diagnostic reliability. These findings have several implications. Given that generalized anxiety disorder is difficult to assess and has a very high comorbidity rate, clinicians may want to systematically assess their level of confidence in their diagnostic impression for patients with GAD. Moreover, if future studies replicate the finding that diagnostic confidence is unrelated to inter-rater agreement for the diagnosis of GAD, we suggest that clinicians should be careful not to conclude that their diagnostic impression is accurate based solely on their level of confidence. Ultimately, continued assessment during therapy remains the best strategy to ensure that the treatment offered is tailored to the patient's condition.

探索TAG严重性评估中诊断置信度和法官间协议之间的联系
当临床医生对他们的诊断印象有很强的信心时,他们的印象是否更准确?本研究旨在探索临床医生的诊断信心与法官间协议评估的诊断印象的准确性之间是否存在联系。我们的假设是:(1)第一次结构化诊断访谈的诊断置信度将与第二次结构化诊断面谈的诊断信任度相关;(2)两次面谈的诊断置信度将预测法官之间的协议。诊断置信度由临床医生进行评估,临床医生对100名被评估参与广泛性焦虑症治疗研究的患者进行了两次独立的结构化诊断访谈。结果显示,两次独立访谈的诊断置信度之间存在统计学显著关系。然而,两次访谈的诊断信心与法官之间的协议无关。当共病疾病的数量被统计控制时,两次访谈的置信度之间的关系不再显著。因此,根据共病疾病的数量,似乎对更容易或更难诊断的临床图表达成了一致。背景:在提供诊断印象时,临床医生以他们的确定感或信心为指导。因此,预计当临床医生对他/她的诊断印象有信心时,后者应该有更大的机会变得可靠。令人惊讶的是,一些医学研究表明,临床医生对其诊断印象的信心水平与诊断的可靠性/有效性之间只有适度的关系。广义焦虑障碍(GAD)是评估和诊断最困难的心理障碍之一。因此,GAD提供了一个独特的机会来检查临床医生诊断信心与其诊断印象的可靠性之间的关系。我们的假设是:(1)初始诊断访谈的诊断信心(DSM-IV焦虑障碍访谈时间表;ADIS-IV)将与第二次独立诊断访谈的诊断信心相关(迷你国际神经精神病访谈;迷你);(2)每次面试的更高诊断信心将与更大的错过者协议相关。方法作为一般焦虑症临床试验的一部分,我们检查了诊断信心是否与评分员间协议相关。诊断信心评级(0-100%)由一组心理学家使用ADIS-IV和一组精神病医生使用MINI提供,随后独立对100名GAD患者进行了访谈。结果相关分析显示,ADIS-IV的诊断信心与MINI的诊断信心之间存在显着关联(r=0.23,p<;0.05)。对ADIS-IV的诊断信心与访谈之间的评分员间协议无关。相反,一项探索性分析表明,共病的数量与每次访谈的诊断信心有关(ADIS-IV:R=-41,p<;001;MINI:R=-36,p<;0.001),共病程度越高,信心越低。最后,共病是指每次访谈中信心水平之间的关系。本研究的结果表明,临床医生倾向于根据存在的共病疾病数量,就哪些病例更容易或更难诊断达成一致。然而,对诊断的信心似乎与诊断可靠性无关。这些发现有几个含义。由于普遍性焦虑障碍难以评估,且共病率非常高,临床医生可能希望系统地评估他们对GAD患者诊断印象的信心水平。此外,如果未来的研究复制了诊断信心与GAD诊断的相互错过协议不相关的发现,我们建议临床医生谨慎不要得出结论,他们的诊断印象完全基于他们的信心水平。最终,治疗期间的持续评估仍然是确保提供的治疗适合患者病情的最佳策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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