M. Edery , J. Goussard , L. Dehennin , R. Scholler , J. Reiffsteck , M.A. Drosdowsky
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引用次数: 103
Abstract
Oestradiol-17β was determined in human breast tumours by radioimmunoassay and gas chromatography-mass spectrometry. Simultaneous determination of the oestradiol and progesterone receptor content was carried out. Oestradiol receptor positive tumours contained a greater statistically significant oestradiol concentration than receptor negative tumours.
Our results indicate that (a) the use of gas chromatography-mass spectrometry is more valid in measuring endogenous oestradiol-17β content, (b) false negative receptor assays due to the presence of endogenous oestrogens are unlikely.
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