Prospects for Using Metagenomic Analysis As a Tool for The Accurate Diagnosis of Capripoxvirus Infections in Farm Animals

IF 0.8 Q3 Engineering

Nanotechnologies in Russia Pub Date : 2023-09-19 DOI:10.1134/S2635167623700222

S. V. Toshchakov, E. V. Grosfeld, A. D. Kozlova, A. S. Krylova, M. V. Patrushev

引用次数: 0

Abstract

Infectious diseases of small domestic ruminants caused by viruses belonging to the Capripoxvirus genus are a serious economic threat. However, the diagnostic tools currently available for these pathogens do not provide sufficient strain information for effective disease control. This can be solved by sequencing and analysis of the full virus genome, which is currently achievable by the use of next generation sequencing technologies followed by metagenomic analysis. This review discusses the biology of Capripoxvirus pathogens, and the diagnostic and disease control tools in the context of introducing metagenomic analysis as the primary tool for pathogen identification.

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应用宏基因组分析作为准确诊断农场动物卡普病毒感染的工具的前景

由狐痘病毒属病毒引起的家畜小反刍动物传染病是严重的经济威胁。然而，目前可用于这些病原体的诊断工具不能为有效的疾病控制提供足够的菌株信息。这可以通过对病毒全基因组进行测序和分析来解决，目前可以通过使用下一代测序技术，然后进行宏基因组分析来实现。本文在介绍宏基因组分析作为主要病原体鉴定工具的背景下，综述了狐痘病毒病原体的生物学、诊断和疾病控制工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nanotechnologies in Russia NANOSCIENCE & NANOTECHNOLOGY-

CiteScore

1.20

自引率

0.00%

发文量

期刊介绍： Nanobiotechnology Reports publishes interdisciplinary research articles on fundamental aspects of the structure and properties of nanoscale objects and nanomaterials, polymeric and bioorganic molecules, and supramolecular and biohybrid complexes, as well as articles that discuss technologies for their preparation and processing, and practical implementation of products, devices, and nature-like systems based on them. The journal publishes original articles and reviews that meet the highest scientific quality standards in the following areas of science and technology studies: self-organizing structures and nanoassemblies; nanostructures, including nanotubes; functional and structural nanomaterials; polymeric, bioorganic, and hybrid nanomaterials; devices and products based on nanomaterials and nanotechnology; nanobiology and genetics, and omics technologies; nanobiomedicine and nanopharmaceutics; nanoelectronics and neuromorphic computing systems; neurocognitive systems and technologies; nanophotonics; natural science methods in a study of cultural heritage items; metrology, standardization, and monitoring in nanotechnology.

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