Nanomaterial surface modification toolkit: Principles, components, recipes, and applications

IF 15.9 1区化学 Q1 CHEMISTRY, PHYSICAL

Advances in Colloid and Interface Science Pub Date : 2023-11-03 DOI:10.1016/j.cis.2023.103035

Sümeyra Vural Kaymaz , Hediyeh Malekzadsani Nobar , Hasan Sarıgül , Caner Soylukan , Lalehan Akyüz , Meral Yüce

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引用次数: 0

Abstract

Surface-functionalized nanostructures are at the forefront of biotechnology, providing new opportunities for biosensors, drug delivery, therapy, and bioimaging applications. The modification of nanostructures significantly impacts the performance and success of various applications by enabling selective and precise targeting. This review elucidates widely practiced surface modification strategies, including click chemistry, cross-coupling, silanization, aldehyde linkers, active ester chemistry, maleimide chemistry, epoxy linkers, and other protein and DNA-based methodologies. We also delve into the application-focused landscape of the nano-bio interface, emphasizing four key domains: therapeutics, biosensing, environmental monitoring, and point-of-care technologies, by highlighting prominent studies. The insights presented herein pave the way for further innovations at the intersection of nanotechnology and biotechnology, providing a useful handbook for beginners and professionals. The review draws on various sources, including the latest research articles (2018-2023), to provide a comprehensive overview of the field.

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纳米材料表面改性工具包：原理、组件、配方和应用。

表面功能化纳米结构处于生物技术的前沿，为生物传感器、药物递送、治疗和生物成像应用提供了新的机会。纳米结构的修饰通过实现选择性和精确的靶向，显著影响各种应用的性能和成功。这篇综述阐述了广泛应用的表面修饰策略，包括点击化学、交叉偶联、硅烷化、醛连接体、活性酯化学、马来酰亚胺化学、环氧连接体以及其他基于蛋白质和DNA的方法。我们还深入研究了纳米生物界面的应用前景，通过突出突出突出的研究，强调了四个关键领域：治疗学、生物传感、环境监测和护理点技术。本文提出的见解为纳米技术和生物技术交叉点的进一步创新铺平了道路，为初学者和专业人士提供了有用的手册。该综述利用了各种来源，包括最新的研究文章（2018-2023），对该领域进行了全面概述。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advances in Colloid and Interface Science 化学-物理化学

CiteScore

28.50

自引率

2.60%

发文量

175

审稿时长

31 days

期刊介绍： "Advances in Colloid and Interface Science" is an international journal that focuses on experimental and theoretical developments in interfacial and colloidal phenomena. The journal covers a wide range of disciplines including biology, chemistry, physics, and technology. The journal accepts review articles on any topic within the scope of colloid and interface science. These articles should provide an in-depth analysis of the subject matter, offering a critical review of the current state of the field. The author's informed opinion on the topic should also be included. The manuscript should compare and contrast ideas found in the reviewed literature and address the limitations of these ideas. Typically, the articles published in this journal are written by recognized experts in the field.