Barker's Hypothesis Among the Global Poor: Positive Long-Term Cardiovascular Effects of in Utero Famine Exposure.

IF 3.6 1区社会学 Q1 DEMOGRAPHY

Demography Pub Date : 2023-12-01 DOI:10.1215/00703370-11052790

Alberto Ciancio, Jere Behrman, Fabrice Kämpfen, Iliana V Kohler, Jürgen Maurer, Victor Mwapasa, Hans-Peter Kohler

引用次数: 0

Abstract

An influential literature on the Developmental Origins of Health and Disease (DOHaD) has documented that poor conditions in utero lead to higher risk of cardiovascular disease at older ages. Evidence from low-income countries (LICs) has hitherto been missing, despite the fact that adverse in utero conditions are far more common in LICs. We find that Malawians exposed in utero to the 1949 Nyasaland famine have better cardiovascular health 70 years later. These findings highlight the potential context specificity of the DOHaD hypothesis, with in utero adversity having different health implications among aging LIC individuals who were exposed to persistent poverty.

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全球穷人中的巴克假说：子宫内饥荒暴露对心血管的长期积极影响。

一篇关于健康与疾病的发育起源（DOHaD）的有影响力的文献记录了子宫内条件差会导致老年人患心血管疾病的风险更高。尽管子宫内不良情况在低收入国家中更为常见，但迄今为止，低收入国家的证据一直缺失。我们发现，在子宫内暴露于1949年尼亚萨兰饥荒的马拉维人，70年后心血管健康状况更好。这些发现突出了DOHaD假说的潜在背景特异性，子宫内逆境对暴露于持续贫困的老年LIC个体的健康影响不同。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Demography DEMOGRAPHY-

CiteScore

5.90

自引率

2.90%

发文量

期刊介绍： Since its founding in 1964, the journal Demography has mirrored the vitality, diversity, high intellectual standard and wide impact of the field on which it reports. Demography presents the highest quality original research of scholars in a broad range of disciplines, including anthropology, biology, economics, geography, history, psychology, public health, sociology, and statistics. The journal encompasses a wide variety of methodological approaches to population research. Its geographic focus is global, with articles addressing demographic matters from around the planet. Its temporal scope is broad, as represented by research that explores demographic phenomena spanning the ages from the past to the present, and reaching toward the future. Authors whose work is published in Demography benefit from the wide audience of population scientists their research will reach. Also in 2011 Demography remains the most cited journal among population studies and demographic periodicals. Published bimonthly, Demography is the flagship journal of the Population Association of America, reaching the membership of one of the largest professional demographic associations in the world.