Gender-affirming hysterectomy in the United States: A comparative outcomes analysis and potential implications for uterine transplantation.

IF 3.4 2区 医学 Q1 DEMOGRAPHY
Perspectives on Sexual and Reproductive Health Pub Date : 2023-12-01 Epub Date: 2023-11-03 DOI:10.1363/psrh.12246
Nicolette V Siringo, Daniel Boczar, Zoe P Berman, Bachar F Chaya, Laura Kimberly, Ricardo Rodriguez Colon, Jorge Trilles, Hilliard Brydges, Eduardo D Rodriguez
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Abstract

Purpose: Hysterectomy is a gynecological procedure sometimes performed as part of the gender-affirming process for transgender and gender-expansive patients assigned female at birth. Our goal was to compare surgical outcomes between patients undergoing gender-affirming hysterectomy and patients undergoing hysterectomy for benign menstrual disorders. We then explored the implications of gender-affirming hysterectomy for uterine transplantation.

Methods: We performed a retrospective cohort study using data from the American College of Surgeons National Surgical Quality Improvement Program database from 2009 through 2018. We identified patients undergoing hysterectomy in the United States based on Current Procedural Terminology code. We used the International Classification of Diseases 9 or 10 codes to identify patients with benign menstrual disorders (non-gender-affirming group) and gender dysphoria (gender-affirming group). We compared patient characteristics and surgical complications.

Results: Of the 40,742 patients that met inclusion criteria, 526 (1.3%) patients were individuals with gender dysphoria. Compared to patients who underwent hysterectomy for benign menstrual disorders, gender-affirming patients were younger, were healthier, had a lower prevalence of diabetes, and were more likely to undergo surgery in the outpatient setting, with shorter time to discharge. Complication rates were similar between groups. Logistic regression controlling for the American Society of Anesthesiology classification determined the difference of return to the operating room was not statistically significant (OR 1.082; 95% CI, 0.56-2.10; p = 0.816).

Conclusion: Gender-affirming hysterectomy has a safety profile similar to hysterectomy performed for benign menstrual disorders. Researchers should further explore the possibility of uterus donation among these patients as they may be suitable candidates.

美国确认性别的子宫切除术:比较结果分析和子宫移植的潜在意义。
目的:子宫切除术是一种妇科手术,有时作为性别确认过程的一部分,适用于出生时被指定为女性的变性和性别膨胀患者。我们的目的是比较接受性别确认子宫切除术的患者和因良性月经障碍而接受子宫切除术患者的手术结果。然后,我们探讨了性别确认子宫切除术对子宫移植的影响。方法:我们使用2009年至2018年美国外科医生学会国家外科质量改进计划数据库的数据进行了一项回顾性队列研究。我们根据当前的手术术语代码确定了在美国进行子宫切除术的患者。我们使用国际疾病分类9或10编码来识别良性月经障碍(非性别确认组)和性别焦虑症(性别确认组。我们比较了患者特征和手术并发症。结果:在符合纳入标准的40742名患者中,526名(1.3%)患者患有性别焦虑症。与因良性月经失调而接受子宫切除术的患者相比,性别确认患者更年轻、更健康、糖尿病患病率更低,更有可能在门诊接受手术,出院时间更短。两组的并发症发生率相似。美国麻醉学会分类的逻辑回归控制确定返回手术室的差异无统计学意义(OR 1.082;95%CI,0.56-2.10;p = 0.816)。结论:性别肯定的子宫切除术具有类似于对良性月经障碍进行子宫切除术的安全性。研究人员应该进一步探索这些患者捐献子宫的可能性,因为他们可能是合适的候选人。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
5.10
自引率
3.40%
发文量
24
期刊介绍: Perspectives on Sexual and Reproductive Health provides the latest peer-reviewed, policy-relevant research and analysis on sexual and reproductive health and rights in the United States and other developed countries. For more than four decades, Perspectives has offered unique insights into how reproductive health issues relate to one another; how they are affected by policies and programs; and their implications for individuals and societies. Published four times a year, Perspectives on Sexual and Reproductive Health includes original research, special reports and commentaries on the latest developments in the field of sexual and reproductive health, as well as staff-written summaries of recent findings in the field.
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