Osteochondral Allograft Transplantation in the Shoulder: A Systematic Review of Indications and Outcomes.

IF 2.7 4区 医学 Q1 ORTHOPEDICS
CARTILAGE Pub Date : 2024-09-01 Epub Date: 2023-11-08 DOI:10.1177/19476035231205678
Brian Prigmore, Suzanne Tabbaa, Dennis C Crawford
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引用次数: 0

Abstract

Objective: To collate current literature pertaining to the published reports of indications for, and outcomes of, osteochondral allograft (OCA) transplantations in the shoulder so as to guide surgeons in the management of various etiologies of osteochondral lesions in this joint.

Design: A systematic review of the current literature was performed in February 2022 in the PubMed, Cochrane, and EMBASE databases using specific search terms and predetermined inclusion/exclusion criteria.

Results: One-hundred-twenty-three articles were initially identified, 30 full-text articles were assessed for eligibility, and 17 articles met inclusion criteria. Data were collected for study characteristics, etiology, lesion size/location, intervention/type of graft used, follow-up, and outcomes. In total, 83 shoulders were included (n = 83) in the review with an average follow-up of 45.7 months. Nine specific indications for OCA transplantation in the shoulder included: reverse Hill-Sachs lesions (33), Hill-Sachs lesions (22), pain pump chondrolysis (10), recurrent shoulder instability (7), osteoarthritis/degenerative changes (5), radiofrequency chondrolysis (2), prominent suture anchors (2), glenoid lesion (1), and osteochondritis dissecans (1). Seventeen patients had concomitant surgeries and two patients were lost to follow-up. Of the total 83 shoulders, 68 had favorable outcomes and 13 had unfavorable outcomes as determined by graft incorporation, pain scores, functionality/ROM, patient-reported satisfaction, and/or requirement for revision/arthroplasty. Of the 13 with unfavorable outcomes, a disproportionate number had concomitant surgeries and/or were performed for pain pump chondrolysis (6).

Conclusions: The use of OCAs appears to be a viable option for a variety of difficult-to-treat shoulder pathologies, particularly those characterized by isolated osteochondral injuries.

肩关节同种异体骨软骨移植:适应证和结果的系统评价。
目的:整理已发表的关于肩关节同种异体骨软骨移植适应症和结果的文献,以指导外科医生处理该关节骨软骨病变的各种病因。设计:2022年2月,在PubMed、Cochrane和EMBASE数据库中,使用特定的搜索词和预先确定的纳入/排除标准,对当前文献进行了系统综述。结果:123篇文章被初步鉴定,30篇全文文章被评估为合格,17篇文章符合纳入标准。收集研究特征、病因、病变大小/位置、干预措施/所用移植物类型、随访和结果的数据。共有83个肩部(n=83)被纳入审查,平均随访45.7个月。OCA移植肩关节的9个具体适应症包括:反向Hill Sachs病变(33)、Hill Sachs损伤(22)、疼痛泵软骨溶解术(10)、复发性肩关节不稳定症(7)、骨关节炎/退行性改变(5)、射频软骨溶解症(2)、突出缝合锚(2),关节盂病变(1)和剥脱性骨软骨炎(1)。17名患者同时进行了手术,2名患者失访。根据移植物结合、疼痛评分、功能/ROM、患者报告的满意度和/或翻修/关节成形术的要求,在总共83个肩部中,68个有良好的结果,13个有不良的结果。在13例结果不佳的患者中,有不成比例的患者同时进行了手术和/或进行了疼痛泵软骨溶解术(6)。结论:对于各种难以治疗的肩部疾病,尤其是以孤立性骨软骨损伤为特征的疾病,使用OCA似乎是一种可行的选择。
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来源期刊
CARTILAGE
CARTILAGE ORTHOPEDICS-
CiteScore
6.90
自引率
7.10%
发文量
80
期刊介绍: CARTILAGE publishes articles related to the musculoskeletal system with particular attention to cartilage repair, development, function, degeneration, transplantation, and rehabilitation. The journal is a forum for the exchange of ideas for the many types of researchers and clinicians involved in cartilage biology and repair. A primary objective of CARTILAGE is to foster the cross-fertilization of the findings between clinical and basic sciences throughout the various disciplines involved in cartilage repair. The journal publishes full length original manuscripts on all types of cartilage including articular, nasal, auricular, tracheal/bronchial, and intervertebral disc fibrocartilage. Manuscripts on clinical and laboratory research are welcome. Review articles, editorials, and letters are also encouraged. The ICRS envisages CARTILAGE as a forum for the exchange of knowledge among clinicians, scientists, patients, and researchers. The International Cartilage Repair Society (ICRS) is dedicated to promotion, encouragement, and distribution of fundamental and applied research of cartilage in order to permit a better knowledge of function and dysfunction of articular cartilage and its repair.
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