Bullous Lichen Planus of the Nails: A Case Report and Review of the Literature.

IF 0.9 Q4 DERMATOLOGY
Case Reports in Dermatology Pub Date : 2023-09-04 eCollection Date: 2023-01-01 DOI:10.1159/000533386
Jonathan K Hwang, Cynthia M Magro, Shari R Lipner
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引用次数: 0

Abstract

Lichen planus is a chronic inflammatory disorder that may affect the skin, nails, and/or oral mucosa. Bullous lichen planus is a rare variant of lichen planus, which is even less common in the nails. We present a case of nail bullous lichen planus, in a 48-year-old male presenting with a 10-month history of onychodystrophy of all ten fingernails. A longitudinal excision of the left thumbnail was performed, with histopathology consistent with lichen planus with focal transition to bullous lichen planus. He was treated with intralesional triamcinolone injections to the fingernails monthly, with improvements noted after three treatments. Our patient's nail bullous lichen planus manifested with longitudinal ridging, white-yellow discoloration, onycholysis, subungual hyperkeratosis, and v-shaped nicking. Histopathological findings included classical lichen planus changes, as well as formation of subepidermal bullae, colloid bodies, and extensive inflammatory infiltrate. Increased awareness and high index of suspicion for this condition are necessary, given the often late diagnosis reported in previously published cases.

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大疱性指甲扁平苔藓一例报告并文献复习。
扁平苔藓是一种慢性炎症性疾病,可能影响皮肤、指甲和/或口腔黏膜。大疱性扁平苔藓是扁平苔藓的一种罕见变种,在指甲中更不常见。我们报告了一例指甲大疱性扁平苔藓,患者为48岁男性,有10个月的甲营养不良病史。对左侧拇指进行了纵向切除,组织病理学与扁平苔藓一致,局灶性转变为大疱性扁平苔藓。他每月在指甲上注射曲安奈德,经过三次治疗后病情有所好转。我们患者的指甲大疱性扁平苔藓表现为纵向隆起、白黄色变色、甲溶解、甲下角化过度和v形切口。组织病理学检查结果包括典型的扁平苔藓变化,以及表皮下大疱、胶体和广泛的炎症浸润的形成。鉴于先前公布的病例中报告的诊断往往较晚,有必要提高对这种情况的认识和高度怀疑。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.60
自引率
0.00%
发文量
57
审稿时长
9 weeks
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