{"title":"Ambient Air Pollution: A New Intrauterine Environmental Toxin for Preterm Birth and Low Birth Weight.","authors":"Neha Bhardwaj, Aruna Nigam, Arpita De, Neha Gupta","doi":"10.1007/s13224-023-01790-8","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Urbanization and industrialization in developing and developed countries have led to rise of intrauterine environmental toxins-PM2.5, PM10, NO<sub>2</sub> and Ozone.</p><p><strong>Aim: </strong>To determine association of ambient air pollution exposure with prematurity and low birth weight.</p><p><strong>Materials and methods: </strong>It is a retrospective cohort study done from January 2021 till June 2022 in a tertiary care hospital, New Delhi. Purposive sampling was done, and for each patient, criteria pollutants exposure was recorded from the government recording stations nearest to her residence and pregnancy outcome correlated with same.</p><p><strong>Results: </strong>Total 1155 deliveries were recruited. Significant association was found between PM2.5 exposure and preterm birth during first trimester (<i>p</i> < 0.05). Significant association was found between ozone exposure and preterm birth during second trimester (<i>p</i> < 0.05). Significant association was also found between NO<sub>2</sub> exposure and preterm birth during first and second trimester (<i>p</i> < 0.05). Maternal PM2.5 exposure during first trimester was significantly associated with low birth weight (<i>p</i> < 0.05). PM10 exposure during first trimester was significantly associated with low birth weight (<i>p</i> < 0.05).</p><p><strong>Conclusion: </strong>Current study reveals direct relationship between ambient air pollution exposure and pregnancy outcomes (preterm birth and low birth weight).</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"73 Suppl 1","pages":"25-29"},"PeriodicalIF":0.7000,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616042/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Obstetrics and Gynecology of India","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s13224-023-01790-8","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/7/19 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Urbanization and industrialization in developing and developed countries have led to rise of intrauterine environmental toxins-PM2.5, PM10, NO2 and Ozone.
Aim: To determine association of ambient air pollution exposure with prematurity and low birth weight.
Materials and methods: It is a retrospective cohort study done from January 2021 till June 2022 in a tertiary care hospital, New Delhi. Purposive sampling was done, and for each patient, criteria pollutants exposure was recorded from the government recording stations nearest to her residence and pregnancy outcome correlated with same.
Results: Total 1155 deliveries were recruited. Significant association was found between PM2.5 exposure and preterm birth during first trimester (p < 0.05). Significant association was found between ozone exposure and preterm birth during second trimester (p < 0.05). Significant association was also found between NO2 exposure and preterm birth during first and second trimester (p < 0.05). Maternal PM2.5 exposure during first trimester was significantly associated with low birth weight (p < 0.05). PM10 exposure during first trimester was significantly associated with low birth weight (p < 0.05).
Conclusion: Current study reveals direct relationship between ambient air pollution exposure and pregnancy outcomes (preterm birth and low birth weight).
背景：发展中国家和发达国家的城市化和工业化导致宫内环境毒素PM2.5、PM10、NO2和臭氧的增加。目的：确定环境空气污染暴露与早产和低出生体重的关系。材料和方法：这是一项从2021年1月到2022年6月在新德里一家三级护理医院进行的回顾性队列研究。对每位患者进行了有针对性的采样，从离其住所最近的政府记录站记录标准污染物暴露情况，并将妊娠结果与之相关。结果：共招募了1155名分娩者。PM2.5暴露与妊娠早期早产之间存在显著相关性（p p 2妊娠早期和中期的暴露和早产（p p p 结论：目前的研究揭示了环境空气污染暴露和妊娠结局（早产和低出生体重）之间的直接关系。
期刊介绍：
Journal of Obstetrics and Gynecology of India (JOGI) is the official journal of the Federation of Obstetrics and Gynecology Societies of India (FOGSI). This is a peer- reviewed journal and features articles pertaining to the field of obstetrics and gynecology. The Journal is published six times a year on a bimonthly basis. Articles contributed by clinicians involved in patient care and research, and basic science researchers are considered. It publishes clinical and basic research of all aspects of obstetrics and gynecology, community obstetrics and family welfare and subspecialty subjects including gynecological endoscopy, infertility, oncology and ultrasonography, provided they have scientific merit and represent an important advance in knowledge. The journal believes in diversity and welcomes and encourages relevant contributions from world over. The types of articles published are: · Original Article· Case Report · Instrumentation and Techniques · Short Commentary · Correspondence (Letter to the Editor) · Pictorial Essay
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