Survival Rate in Cancer Cervix Patients in a Regional Cancer Centre of South India: A Retrospective Analysis.

IF 0.7 Q4 OBSTETRICS & GYNECOLOGY
Sakthi Usha Devi Jeevarajan, Prasanna Srinivasa Rao Harikrishnan, T D Balamurugan, Ajay Kumar Arunachalam
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引用次数: 0

Abstract

Context: Carcinoma Cervix is one of the leading prevalent cancers in India especially in rural population and causes a significant mortality. WHO has launched many projects for prevention, screening and treatment plans. Even after many projects, Cervical Cancer persists as a heavy burden public health problem in rural India.

Aims: To calculate survival of cancer cervix patients in a rural population-based RCC and to discuss the factors affecting it.

Methods and material: A hospital-based gathering of retrospective data of the patients diagnosed with carcinoma cervix over 5 years from January 2013 to December 2017 (single institution analysis). We included 751 patient's data from our cancer registry for analysis. Data related to demographics, treatment and follow up records were taken and statistical analysis done.

Results: The survival rates were 64.0%, 50.0%, 36.9% and 17.5% for Stage I, Stage II, Stage III and Stage IV, respectively. The best survival outcomes were for those treated with only surgery. Involvement of nodes had poor survival than those with no involvement. Various patient-related factors like Religion, Education and Marital status are found to be non-significant factors even-though they have survival differences. STAGE of the disease emerged as a significant prognostic factor.

Conclusion: Our study concluded that higher stage and nodal involvement had poor outcomes and also lower survival compared to Western and Indian literature. We should also address all the socio-economic factors that affects survival. Randomized prospective studies are needed to evaluate the effect of socio-economic factors on survival.

南印度癌症地区中心癌症宫颈患者的生存率:回顾性分析。
背景:宫颈癌是印度最常见的癌症之一,尤其是在农村人口中,并导致显著的死亡率。世界卫生组织启动了许多预防、筛查和治疗计划项目。即使在许多项目之后,癌症宫颈癌在印度农村仍然是一个沉重的公共卫生问题。目的:计算癌症宫颈癌患者在农村人群碾压混凝土中的生存率,并讨论影响其生存的因素。方法和材料:2013年1月至2017年12月5年来诊断为宫颈癌的患者的医院回顾性数据收集(单一机构分析)。我们纳入了来自癌症登记处的751名患者的数据进行分析。收集与人口统计、治疗和随访记录相关的数据,并进行统计分析。结果:Ⅰ期、Ⅱ期、Ⅲ期和Ⅳ期的生存率分别为64.0%、50.0%、36.9%和17.5%。最好的生存结果是那些只接受手术治疗的患者。有淋巴结受累的患者生存率低于无淋巴结受累者。宗教、教育和婚姻状况等各种与患者相关的因素被发现是非显著因素,尽管它们存在生存差异。疾病的分期成为一个重要的预后因素。结论:我们的研究得出结论,与西方和印度文献相比,高分期和淋巴结受累的预后较差,生存率也较低。我们还应该处理影响生存的所有社会经济因素。需要进行随机前瞻性研究来评估社会经济因素对生存率的影响。
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来源期刊
CiteScore
1.30
自引率
0.00%
发文量
124
期刊介绍: Journal of Obstetrics and Gynecology of India (JOGI) is the official journal of the Federation of Obstetrics and Gynecology Societies of India (FOGSI). This is a peer- reviewed journal and features articles pertaining to the field of obstetrics and gynecology. The Journal is published six times a year on a bimonthly basis. Articles contributed by clinicians involved in patient care and research, and basic science researchers are considered. It publishes clinical and basic research of all aspects of obstetrics and gynecology, community obstetrics and family welfare and subspecialty subjects including gynecological endoscopy, infertility, oncology and ultrasonography, provided they have scientific merit and represent an important advance in knowledge. The journal believes in diversity and welcomes and encourages relevant contributions from world over. The types of articles published are: ·         Original Article·         Case Report ·         Instrumentation and Techniques ·         Short Commentary ·         Correspondence (Letter to the Editor) ·         Pictorial Essay
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