The effect of epigallocatechin gallate on laying performance, egg quality, immune status, antioxidant capacity, and hepatic metabolome of laying ducks reared in high temperature condition.

IF 7.9 2区 农林科学 Q1 VETERINARY SCIENCES
Veterinary Quarterly Pub Date : 2023-12-01 Epub Date: 2023-11-15 DOI:10.1080/01652176.2023.2280041
Yang Liu, Xu Zhang, Yaling Yao, Xuan Huang, Chuang Li, Ping Deng, Guitao Jiang, Qiuzhong Dai
{"title":"The effect of epigallocatechin gallate on laying performance, egg quality, immune status, antioxidant capacity, and hepatic metabolome of laying ducks reared in high temperature condition.","authors":"Yang Liu, Xu Zhang, Yaling Yao, Xuan Huang, Chuang Li, Ping Deng, Guitao Jiang, Qiuzhong Dai","doi":"10.1080/01652176.2023.2280041","DOIUrl":null,"url":null,"abstract":"<p><p>Epigallocatechin gallate (EGCG) is a main component in green tea extract, which possesses multiple bioactivities. The present research studied the effects of EGCG on the laying performance, egg quality, immune status, antioxidant capacity, and hepatic metabolome of <i>Linwu</i> laying ducks reared under high temperature. A total of 180 42-w-old healthy <i>Linwu</i> laying ducks were allocated into control or EGCG-treated groups. Each treatment had 6 replicates with 15 ducks in each replicate. Diets for the two groups were basal diets supplemented with 0 or 300 mg/kg EGCG, respectively. All ducks were raised in the high temperature condition (35 ± 2 °C for 6 h from 10:00 to 16:00, and 28 ± 2 °C for the other 18 h from 16:00 to 10:00 the next day) for 21 days. Results showed that EGCG increased the egg production rate (<i>p</i> = 0.014) and enhanced the immunocompetence by improving serum levels of immunoglobulin A (<i>p</i> = 0.008) and immunoglobulin G (<i>p</i> = 0.006). EGCG also fortified the antioxidant capacity by activating superoxide dismutase (<i>p</i> = 0.012), catalase (<i>p</i> = 0.009), and glutathione peroxidase (<i>p</i> = 0.021), and increasing the level of heat-shock protein 70 (<i>p</i> = 0.003) in laying ducks' liver. At the same time, hepatic metabolomics result suggested that EGCG increased the concentration of several key metabolites, such as spermidine (<i>p</i> = 0.031), tetramethylenediamine (<i>p</i> = 0.009), hyoscyamine (<i>p</i> = 0.026), β-nicotinamide adenine dinucleotide phosphate (<i>p</i> = 0.038), and pantothenic acid (<i>p</i> = 0.010), which were involved in the metabolic pathways of glutathione metabolism, arginine and proline metabolism, β-alanine metabolism, and tropane, piperidine, and pyridine alkaloid biosynthesis. In conclusion, 300 mg/kg dietary EGCG showed protection effects on the laying ducks reared in high temperature by improving the immune and antioxidant capacities, which contributed to the increase of laying performance of ducks. The potential mechanism could be that EGCG modulate the synthesis of key metabolites and associated metabolic pathways.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":null,"pages":null},"PeriodicalIF":7.9000,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11003483/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Veterinary Quarterly","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1080/01652176.2023.2280041","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/11/15 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0

Abstract

Epigallocatechin gallate (EGCG) is a main component in green tea extract, which possesses multiple bioactivities. The present research studied the effects of EGCG on the laying performance, egg quality, immune status, antioxidant capacity, and hepatic metabolome of Linwu laying ducks reared under high temperature. A total of 180 42-w-old healthy Linwu laying ducks were allocated into control or EGCG-treated groups. Each treatment had 6 replicates with 15 ducks in each replicate. Diets for the two groups were basal diets supplemented with 0 or 300 mg/kg EGCG, respectively. All ducks were raised in the high temperature condition (35 ± 2 °C for 6 h from 10:00 to 16:00, and 28 ± 2 °C for the other 18 h from 16:00 to 10:00 the next day) for 21 days. Results showed that EGCG increased the egg production rate (p = 0.014) and enhanced the immunocompetence by improving serum levels of immunoglobulin A (p = 0.008) and immunoglobulin G (p = 0.006). EGCG also fortified the antioxidant capacity by activating superoxide dismutase (p = 0.012), catalase (p = 0.009), and glutathione peroxidase (p = 0.021), and increasing the level of heat-shock protein 70 (p = 0.003) in laying ducks' liver. At the same time, hepatic metabolomics result suggested that EGCG increased the concentration of several key metabolites, such as spermidine (p = 0.031), tetramethylenediamine (p = 0.009), hyoscyamine (p = 0.026), β-nicotinamide adenine dinucleotide phosphate (p = 0.038), and pantothenic acid (p = 0.010), which were involved in the metabolic pathways of glutathione metabolism, arginine and proline metabolism, β-alanine metabolism, and tropane, piperidine, and pyridine alkaloid biosynthesis. In conclusion, 300 mg/kg dietary EGCG showed protection effects on the laying ducks reared in high temperature by improving the immune and antioxidant capacities, which contributed to the increase of laying performance of ducks. The potential mechanism could be that EGCG modulate the synthesis of key metabolites and associated metabolic pathways.

表没食子儿茶素没食子酸盐对高温条件下蛋鸡产蛋性能、蛋品质、免疫状态、抗氧化能力和肝脏代谢组的影响。
表没食子儿茶素没食子酸盐(EGCG)是绿茶提取物中的主要成分,具有多种生物活性。研究了EGCG对临武蛋鸡高温饲养性能、蛋品质、免疫状态、抗氧化能力和肝脏代谢组的影响。将180只42周龄的健康临武蛋鸡分为对照组或EGCG处理组。每个处理有6个重复,每个重复中有15只鸭子。两组的日粮为基础日粮,添加0或300 mg/kg EGCG。所有鸭子都是在高温条件下饲养的(35 ± 2. °C持续6 h 10:00至16:00和28 ± 2. 其他18°C h从16:00到次日10:00),持续21天。结果表明,EGCG能提高产蛋率(P = 0.014),并通过提高血清免疫球蛋白A(P = 0.008)和免疫球蛋白G(P = EGCG还通过激活超氧化物歧化酶增强抗氧化能力(P = 0.012)、过氧化氢酶(P = 0.009)和谷胱甘肽过氧化物酶(P = 0.021),并使热休克蛋白70水平升高(P = 0.003)。同时,肝脏代谢组学结果表明,EGCG增加了亚精胺等几种关键代谢产物的浓度(P = 0.031)、四亚甲基二胺(P = 0.009)、山莨菪碱(P = 0.026)、β-烟酰胺腺嘌呤二核苷酸磷酸(P = 0.038)和泛酸(P = 0.010),参与谷胱甘肽代谢、精氨酸和脯氨酸代谢、β-丙氨酸代谢以及tropane、哌啶和吡啶生物碱生物合成的代谢途径。总之,300 mg/kg日粮EGCG对高温饲养的产蛋鸭具有保护作用,可提高其免疫和抗氧化能力,有助于提高产蛋性能。潜在的机制可能是EGCG调节关键代谢产物和相关代谢途径的合成。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Veterinary Quarterly
Veterinary Quarterly VETERINARY SCIENCES-
CiteScore
13.10
自引率
1.60%
发文量
18
审稿时长
>24 weeks
期刊介绍: Veterinary Quarterly is an international open access journal which publishes high quality review articles and original research in the field of veterinary science and animal diseases. The journal publishes research on a range of different animal species and topics including: - Economically important species such as domesticated and non-domesticated farm animals, including avian and poultry diseases; - Companion animals (dogs, cats, horses, pocket pets and exotics); - Wildlife species; - Infectious diseases; - Diagnosis; - Treatment including pharmacology and vaccination
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信