Impact of Rose Water Mouthwash on Prevention of Ventilator-Associated Pneumonia in Intensive Care Unit: A Randomized Controlled Trial.

Q3 Medicine
Tanaffos Pub Date : 2023-01-01
Faramarz Dobakhti, Mahsa Eskandari, Mahdi Tavakolizadeh, Narges Forouzideh, Parmida Dobakhti, Mohammadreza Jamshidi, Taraneh Naghibi
{"title":"Impact of Rose Water Mouthwash on Prevention of Ventilator-Associated Pneumonia in Intensive Care Unit: A Randomized Controlled Trial.","authors":"Faramarz Dobakhti,&nbsp;Mahsa Eskandari,&nbsp;Mahdi Tavakolizadeh,&nbsp;Narges Forouzideh,&nbsp;Parmida Dobakhti,&nbsp;Mohammadreza Jamshidi,&nbsp;Taraneh Naghibi","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Preventing Ventilator- Associated Pneumonia (VAP) is an important strategy to increase the quality of provided care for patients under mechanical ventilation. Rose water is the main product of <i>Rosa damascena</i> which is a popular medicinal plant and has been widely used in alternative medicine. It has antibacterial activity against gram-negative and gram-positive bacteria which can potentially cause VAP.</p><p><strong>Materials and methods: </strong>This study was a randomized, controlled, single-center trial. 88 patients in a 21-bed surgical Intensive Care Unit (ICU) who were under mechanical ventilation met the inclusion criteria, and 80 patients fulfilled the study. Based on receiving either rose water and chlorhexidine solution or chlorhexidine solution alone, the patients were divided into two groups of control and intervention. The incidence of VAP up to 14 days was the primary outcome. Duration of mechanical ventilation, the ICU length of stay, and mortality in ICU were the secondary outcomes.</p><p><strong>Results: </strong>There was no significant difference in demographic data, the incidence of VAP, the incidence of late-onset VAP, mechanical ventilation days, length of the ICU stay, and mortality between the two groups. However, the incidence of early-onset VAP in the intervention group was significantly lower than in the control group (p= 0.021).</p><p><strong>Conclusion: </strong>Rose water mouthwash significantly reduced the risk of early-onset VAP without any effect on late-onset VAP.</p>","PeriodicalId":22247,"journal":{"name":"Tanaffos","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618586/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tanaffos","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Preventing Ventilator- Associated Pneumonia (VAP) is an important strategy to increase the quality of provided care for patients under mechanical ventilation. Rose water is the main product of Rosa damascena which is a popular medicinal plant and has been widely used in alternative medicine. It has antibacterial activity against gram-negative and gram-positive bacteria which can potentially cause VAP.

Materials and methods: This study was a randomized, controlled, single-center trial. 88 patients in a 21-bed surgical Intensive Care Unit (ICU) who were under mechanical ventilation met the inclusion criteria, and 80 patients fulfilled the study. Based on receiving either rose water and chlorhexidine solution or chlorhexidine solution alone, the patients were divided into two groups of control and intervention. The incidence of VAP up to 14 days was the primary outcome. Duration of mechanical ventilation, the ICU length of stay, and mortality in ICU were the secondary outcomes.

Results: There was no significant difference in demographic data, the incidence of VAP, the incidence of late-onset VAP, mechanical ventilation days, length of the ICU stay, and mortality between the two groups. However, the incidence of early-onset VAP in the intervention group was significantly lower than in the control group (p= 0.021).

Conclusion: Rose water mouthwash significantly reduced the risk of early-onset VAP without any effect on late-onset VAP.

Abstract Image

玫瑰水漱口液对重症监护室预防呼吸机相关性肺炎的影响:一项随机对照试验。
背景:预防呼吸机相关性肺炎(VAP)是提高机械通气患者护理质量的重要策略。玫瑰水是大马士革罗莎的主要产品,大马士革罗莎是一种受欢迎的药用植物,在替代医学中有着广泛的应用。它对可能导致VAP的革兰氏阴性菌和革兰氏阳性菌具有抗菌活性。材料和方法:本研究为随机、对照、单中心试验。在一个拥有21张床位的外科重症监护室(ICU)中,88名接受机械通气的患者符合纳入标准,80名患者符合研究要求。根据接受玫瑰水和氯己定溶液或单独使用氯己定,将患者分为对照组和干预组。VAP发生率达14天是主要结果。机械通气持续时间、ICU住院时间和ICU死亡率是次要结果。结果:两组在人口统计学数据、VAP发病率、晚发性VAP发生率、机械通气天数、ICU住院时间和死亡率方面没有显著差异。然而,干预组早发性VAP的发生率显著低于对照组(p=0.021)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Tanaffos
Tanaffos Medicine-Critical Care and Intensive Care Medicine
CiteScore
1.10
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信