Muscle strength, not muscle mass, determines the health-related quality of life in Indonesian women with systemic lupus erythematosus.

IF 3.7 2区医学 Q1 RHEUMATOLOGY

Lupus Science & Medicine Pub Date : 2023-11-01 DOI:10.1136/lupus-2023-001025

Stevent Sumantri, Euphemia Seto, Iris Rengganis

{"title":"Muscle strength, not muscle mass, determines the health-related quality of life in Indonesian women with systemic lupus erythematosus.","authors":"Stevent Sumantri, Euphemia Seto, Iris Rengganis","doi":"10.1136/lupus-2023-001025","DOIUrl":null,"url":null,"abstract":"Objective: No study evaluated the impact of low muscle strength and mass on the Sarcopenia-related Quality of Life (SarQoL) in women with SLE.Methods: This cross-sectional study recruited 145 women with SLE consecutively; muscle strength was measured with a calibrated Jamar handheld dynamometer, muscle mass was measured with appendicular muscle mass index (Tanita MC-780 MAP body impedance analyser) and health-related quality of life with SarQoL Questionnaire. The cut-off points for low muscle strength, low muscle mass and sarcopenia were derived from the Asian Working Group on Sarcopenia 2019. Statistical analysis was conducted with a t-test for mean difference, and logistic regression was used to evaluate for low muscle strength contributing factors.Results: There was a significant difference in the mean total score of SarQoL in individuals with normal compared with low muscle strength (74.36 vs 64.85; mean difference 9.50; 95% CI 2.10 to 5.33; p<0.001). On the other hand, there was no difference in individuals with normal compared with low muscle mass (71.07 vs 70.79; mean difference 0.28; -5.18 to 5.74; p=0.91). After minimally adjusted with age, we found moderate-severe joint pain (B -9.280; p<0.001) and low muscle strength (B -6.979; p=0.001) to be independently associated with low mean SarQoL total score.Conclusion: There was a lower total SarQoL score in individuals with low muscle strength but not with low muscle mass.","PeriodicalId":18126,"journal":{"name":"Lupus Science & Medicine","volume":"10 2","pages":""},"PeriodicalIF":3.7000,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626751/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Lupus Science & Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1136/lupus-2023-001025","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"RHEUMATOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: No study evaluated the impact of low muscle strength and mass on the Sarcopenia-related Quality of Life (SarQoL) in women with SLE.

Methods: This cross-sectional study recruited 145 women with SLE consecutively; muscle strength was measured with a calibrated Jamar handheld dynamometer, muscle mass was measured with appendicular muscle mass index (Tanita MC-780 MAP body impedance analyser) and health-related quality of life with SarQoL Questionnaire. The cut-off points for low muscle strength, low muscle mass and sarcopenia were derived from the Asian Working Group on Sarcopenia 2019. Statistical analysis was conducted with a t-test for mean difference, and logistic regression was used to evaluate for low muscle strength contributing factors.

Results: There was a significant difference in the mean total score of SarQoL in individuals with normal compared with low muscle strength (74.36 vs 64.85; mean difference 9.50; 95% CI 2.10 to 5.33; p<0.001). On the other hand, there was no difference in individuals with normal compared with low muscle mass (71.07 vs 70.79; mean difference 0.28; -5.18 to 5.74; p=0.91). After minimally adjusted with age, we found moderate-severe joint pain (B -9.280; p<0.001) and low muscle strength (B -6.979; p=0.001) to be independently associated with low mean SarQoL total score.

Conclusion: There was a lower total SarQoL score in individuals with low muscle strength but not with low muscle mass.

查看原文本刊更多论文

决定印尼系统性红斑狼疮患者健康生活质量的是肌肉力量，而不是肌肉质量。

目的：没有研究评估低肌肉力量和低质量对系统性红斑狼疮（SLE）妇女与肌肉萎缩相关的生活质量（SarQoL）的影响。方法：本横断面研究连续招募了145名SLE患者；用校准的Jamar手持式测功机测量肌肉力量，用阑尾肌肉质量指数（Tanita MC-780 MAP身体阻抗分析仪）测量肌肉质量，用SarQoL问卷测量健康相关的生活质量。低肌肉力量、低肌肉量和少肌症的分界点来自2019年亚洲少肌症工作组。统计分析采用t检验平均差异，逻辑回归用于评估低肌肉力量的影响因素。结果：与低肌肉力量相比，正常个体的SarQoL平均总分有显著差异（74.36 vs 64.85；平均差异9.50；95%CI 2.10至5.33；P结论：低肌肉力量但不低肌肉质量的个体的SarQoL总分较低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Lupus Science & Medicine RHEUMATOLOGY-

CiteScore

5.30

自引率

7.70%

发文量

审稿时长

15 weeks

期刊介绍： Lupus Science & Medicine is a global, peer reviewed, open access online journal that provides a central point for publication of basic, clinical, translational, and epidemiological studies of all aspects of lupus and related diseases. It is the first lupus-specific open access journal in the world and was developed in response to the need for a barrier-free forum for publication of groundbreaking studies in lupus. The journal publishes research on lupus from fields including, but not limited to: rheumatology, dermatology, nephrology, immunology, pediatrics, cardiology, hepatology, pulmonology, obstetrics and gynecology, and psychiatry.