The Fate of Angiotensin II in Placental Tissue and Blood.

IF 2 4区医学 Q3 ENDOCRINOLOGY & METABOLISM

Hormone and Metabolic Research Pub Date : 2024-07-01 Epub Date: 2023-11-01 DOI:10.1055/a-2202-3894

Shigehiko Mizutani, Hidesuke Mizutani, Eita Mizutani, Harumasa Arita, Hiroaki Kajiyama

引用次数: 0

Abstract

The existence of a non-canonical pathway of renin-angiotensin system in the blood pressure control system has been highlighted over the past three decades. The enzymes involved in this pathway include a series of angiotensinases such as neprilysin (NEP), aminopeptidase A (APA), carboxypeptidase, and angiotensin converting enzyme 2. The physiological roles of these peptidases have been reconsidered in this study, based on the publications of other research groups and the results from our previous study, regarding the liberation of constituent amino acids from angiotensin II by placenta tissue and blood serum, respectively.

查看原文本刊更多论文

胎盘组织和血液中血管紧张素II的命运。

在过去的三十年里，肾素-血管紧张素系统在血压控制系统中的非经典途径的存在已经得到了强调。参与该途径的酶包括一系列血管紧张素酶，如奈普赖氨酸（NEP）、氨基肽酶a（APA）、羧肽酶和血管紧张素转换酶2。根据其他研究小组的出版物和我们之前的研究结果，本研究重新考虑了这些肽酶的生理作用，即胎盘组织和血清分别从血管紧张素II中释放组成氨基酸。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Hormone and Metabolic Research 医学-内分泌学与代谢

CiteScore

3.80

自引率

0.00%

发文量

125

审稿时长

3-8 weeks

期刊介绍： Covering the fields of endocrinology and metabolism from both, a clinical and basic science perspective, this well regarded journal publishes original articles, and short communications on cutting edge topics. Speedy publication time is given high priority, ensuring that endocrinologists worldwide get timely, fast-breaking information as it happens. Hormone and Metabolic Research presents reviews, original papers, and short communications, and includes a section on Innovative Methods. With a preference for experimental over observational studies, this journal disseminates new and reliable experimental data from across the field of endocrinology and metabolism to researchers, scientists and doctors world-wide.