Repeat Surgery for Vestibular Schwannomas: An Institutional Case Series.

IF 0.6 Q4 CLINICAL NEUROLOGY
Journal of Neurological Surgery Reports Pub Date : 2023-10-27 eCollection Date: 2023-10-01 DOI:10.1055/s-0043-1776124
Khizar R Nandoliya, Emily J Winterhalter, Constantine L Karras, Rushmin Khazanchi, Mark W Youngblood, Pavlos Texakalidis, James P Chandler, Stephen T Magill
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Abstract

Introduction  Vestibular schwannomas (VSs) are treated with microsurgery and/or radiosurgery. Repeat resection is rare, and few studies have reported postoperative outcomes. The objective of this study was to describe clinical characteristics and outcomes in patients undergoing repeat surgery for VS. Methods  All adult (≥ 18 years) patients undergoing VS resection between 2003 and 2022 at our institution were retrospectively reviewed to identify patients who underwent repeat surgery of an ipsilateral VS following prior gross-total (GTR) or subtotal resection. Patient, radiographic, and clinical characteristics were reviewed. Primary outcomes were postoperative tumor volume, extent of resection, postoperative cranial nerve deficits, and time to further tumor progression. Results  Of 102 patients undergoing VS resection, 6 (5.9%) had undergone repeat surgery. Median (range) follow-up was 20 (5-117) months. Three patients were female. Median age was 56 (36-60) years. Median pre- and postoperative tumor volumes were 8.2 (1.8-28.2) cm 3 and 0.4 (0-3.8) cm 3 . GTR was achieved in two patients. Four patients had higher House-Brackmann scores at last follow-up, but none had tumor progression. Conclusion  In this small cohort of patients, repeat resection of recurrent or progressive VS can effectively reduce tumor volume with acceptable perioperative outcomes.

前庭神经鞘瘤的重复手术:一个机构案例系列。
介绍 前庭神经鞘瘤(VS)采用显微外科和/或放射外科治疗。重复切除是罕见的,很少有研究报告术后结果。本研究的目的是描述接受室间隔缺损重复手术的患者的临床特征和结果 我们对2003年至2022年间在我们机构接受VS切除术的所有成年(≥18岁)患者进行了回顾性审查,以确定在先前的总切除术(GTR)或次全切除术后接受同侧VS重复手术的患者。回顾了患者、放射学和临床特征。主要结果是术后肿瘤体积、切除程度、术后颅神经缺损和肿瘤进一步进展的时间。后果 在接受VS切除术的102名患者中,有6名(5.9%)接受了重复手术。中位(范围)随访时间为20(5-117)个月。三名患者为女性。中位年龄为56岁(36-60岁)。术前和术后肿瘤体积中位数分别为8.2(1.8-28.2)cm3和0.4(0-3.8)cm3。两名患者获得GTR。四名患者在最后一次随访中House Brackmann评分较高,但没有一名患者出现肿瘤进展。结论 在这一小部分患者中,重复切除复发性或进行性VS可以有效地减少肿瘤体积,并具有可接受的围手术期结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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