Examination of late stage elderly patients with oral cancer who were classified as prefrail （vulnerable）

Abstract

Examination of late stage elderly patients with oral cancer who were classified as prefrail （vulnerable）: We examined 23 prefrail （vulnerable） patients among patients with late-stage elderly oral cancer treated in our department. The 5-year overall survival rate was 41.9%, and when classified according to treatment approach, the survival rate was higher in the group that received absolute curative treatment （standard treatment）. Uni-variate analysis of each factor affecting prognosis showed significant differences in G8 score （p=0.047） and stage （p=0.022）, and treatment approach （p=0.052） also tended to affect prognosis. In the results of multivariate analysis, only therapeutic approach was extracted as a factor that significantly affected prognosis （p=0.034）. In addition, decision tree analysis showed that the G8 score was divided into 14 points or more and less than 14 points, suggesting that it may be a predictor of prognosis. Prefrail （vulnerable） is a conceptual category in which it is difficult to apply standard treatment, but it is thought that aiming for standard treatment without easily reducing the treatment intensity will lead to improvement in prognosis. In addition, it is considered useful to use the G8 screening tool as a patient evaluation method.