Clinical analysis of palliative care alone in end-stage head and neck cancer treatment

Q4 Medicine
T. Wakasugi, Fumiko Takenaga, S. Ikezaki, S. Takeuchi, J. Ohkubo, Hideaki Suzuki
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引用次数: 0

Abstract

There are only a few reports on the terminal clinical course of patients who received palliative care alone. We retrospectively analyzed the clinical records of 130 patients with head and neck cancer who accepted a policy of palliative care alone at our institute between March 2008 and February 2018. Median overall survival (OS) was 3.6 months. Patients’ age, histological type, primary site, palliative treatment or use of opioids did not influence OS. On the other hand, OS was significantly shorter in patients with distant metastasis (p = 0.004), those who had received second-line chemotherapy (p = 0.033), intervention by the palliative care team (p = 0.023), those with steroid use (p = 0.005), and those who spent their terminal period in our hospital (p = 0.005). A significant correlation was found between the palliative treatment period and the total period of terminal care (r = 0.631, p < 0.0001). These results suggest that longer palliative treatment may extend the entire course of the terminal period. Since the survival period of patients with head and neck cancers under palliative care alone is generally short, patients’ quality of life is the most important issue to be addressed in this period.
姑息治疗在终末期头颈癌治疗中的临床分析
只有少数报告的病人谁接受姑息治疗的最终临床过程单独。我们回顾性分析了2008年3月至2018年2月期间在我们研究所接受姑息治疗政策的130例头颈癌患者的临床记录。中位总生存期(OS)为3.6个月。患者的年龄、组织学类型、原发部位、姑息治疗或阿片类药物的使用对OS没有影响。另一方面,远处转移患者(p = 0.004)、接受过二线化疗(p = 0.033)、姑息治疗小组干预(p = 0.023)、使用类固醇(p = 0.005)和在我院度过末期的患者(p = 0.005)的OS明显较短。姑息治疗时间与总末期护理时间有显著相关(r = 0.631, p < 0.0001)。这些结果表明,较长的姑息治疗可能延长整个过程的终末期。由于单纯姑息治疗的头颈癌患者生存期普遍较短,患者的生活质量是这一时期最需要解决的问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Japanese Journal of Head and Neck Cancer
Japanese Journal of Head and Neck Cancer Medicine-Otorhinolaryngology
CiteScore
0.10
自引率
0.00%
发文量
7
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